Eisenmenger’s syndrome historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]
Overview
Historical Perspective
Eisenmenger syndrome was initially described in 1897, when Victor Eisenmenger reported on a patient with symptoms of dyspnea and cyanosis from infancy who subsequently developed heart failure and succumbed to massive hemoptysis.[1] An autopsy revealed a large ventricular septal defect (VSD) and an overriding aorta. This was the first description of a link between a large congenital cardiac shunt defect and the development of pulmonary hypertension.
Advances in the medical treatment of patients with severe pulmonary hypertension may improve survival in patients with Eisenmenger syndrome and may potentially reverse the process in selected patients to a point at which they again become candidates for surgical repair.[2]
References
- ↑ Eisenmenger, Vector (1897). "Die angeborenens Defecte der Kammerschieidewand des Herzen". Z Klin Med. 32: I-28.
- ↑ Beghetti M, Galiè N (2009). "Eisenmenger syndrome a clinical perspective in a new therapeutic era of pulmonary arterial hypertension". J Am Coll Cardiol. 53 (9): 733–40. doi:10.1016/j.jacc.2008.11.025. PMID 19245962.