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{{Infobox_gene}}
{{PBB_Controls
'''ETS translocation variant 1''' is a [[protein]] that in humans is encoded by the ''ETV1'' [[gene]].<ref name="pmid1340465">{{cite journal | vauthors = Brown TA, McKnight SL | title = Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins | journal = Genes & Development | volume = 6 | issue = 12B | pages = 2502–12 | date = Dec 1992 | pmid = 1340465 | pmc =  | doi = 10.1101/gad.6.12b.2502 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ETV1 ets variant gene 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2115| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== References ==
{{GNF_Protein_box
{{reflist}}
| image = 
| image_source = 
| PDB =
| Name = Ets variant gene 1
| HGNCid = 3490
| Symbol = ETV1
| AltSymbols =; DKFZp781L0674; ER81; MGC104699; MGC120533; MGC120534
| OMIM = 600541
| ECnumber = 
| Homologene = 3636
| MGIid = 99254
| GeneAtlas_image1 = PBB_GE_ETV1_217061_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_ETV1_206501_x_at_tn.png
| GeneAtlas_image3 = PBB_GE_ETV1_217053_x_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2115
    | Hs_Ensembl = ENSG00000006468
    | Hs_RefseqProtein = NP_004947
    | Hs_RefseqmRNA = NM_004956
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 13897379
    | Hs_GenLoc_end = 13995289
    | Hs_Uniprot = P50549
    | Mm_EntrezGene = 14009
    | Mm_Ensembl = ENSMUSG00000004151
    | Mm_RefseqmRNA = NM_007960
    | Mm_RefseqProtein = NP_031986
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 39290733
    | Mm_GenLoc_end = 39377695
    | Mm_Uniprot = Q549J8
  }}
}}
'''Ets variant gene 1''', also known as '''ETV1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ETV1 ets variant gene 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2115| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Monté D, Coutte L, Baert JL, Angeli I, Stéhelin D, de Launoit Y | title = Molecular characterization of the ets-related human transcription factor ER81 | journal = Oncogene | volume = 11 | issue = 4 | pages = 771–9 | date = Aug 1995 | pmid = 7651741 | doi =  }}
| citations =
* {{cite journal | vauthors = Jeon IS, Davis JN, Braun BS, Sublett JE, Roussel MF, Denny CT, Shapiro DN | title = A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1 | journal = Oncogene | volume = 10 | issue = 6 | pages = 1229–34 | date = Mar 1995 | pmid = 7700648 | doi =  }}
*{{cite journal  | author=Brown TA, McKnight SL |title=Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. |journal=Genes Dev. |volume=6 |issue= 12B |pages= 2502-12 |year= 1993 |pmid= 1340465 |doi=  }}
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = Apr 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
*{{cite journal | author=Monté D, Coutte L, Baert JL, ''et al.'' |title=Molecular characterization of the ets-related human transcription factor ER81. |journal=Oncogene |volume=11 |issue= 4 |pages= 771-9 |year= 1995 |pmid= 7651741 |doi=  }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = Apr 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal | author=Jeon IS, Davis JN, Braun BS, ''et al.'' |title=A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. |journal=Oncogene |volume=10 |issue= 6 |pages= 1229-34 |year= 1995 |pmid= 7700648 |doi=  }}
* {{cite journal | vauthors = Carrère S, Verger A, Flourens A, Stehelin D, Duterque-Coquillaud M | title = Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains | journal = Oncogene | volume = 16 | issue = 25 | pages = 3261–8 | date = Jun 1998 | pmid = 9681824 | doi = 10.1038/sj.onc.1201868 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Coutte L, Monté D, Imai K, Pouilly L, Dewitte F, Vidaud M, Adamski J, Baert JL, de Launoit Y | title = Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human | journal = Oncogene | volume = 18 | issue = 46 | pages = 6278–86 | date = Nov 1999 | pmid = 10597226 | doi = 10.1038/sj.onc.1203020 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
* {{cite journal | vauthors = Janknecht R | title = Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2 | journal = The Journal of Biological Chemistry | volume = 276 | issue = 45 | pages = 41856–61 | date = Nov 2001 | pmid = 11551945 | doi = 10.1074/jbc.M106630200 }}
*{{cite journal | author=Carrère S, Verger A, Flourens A, ''et al.'' |title=Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains. |journal=Oncogene |volume=16 |issue= 25 |pages= 3261-8 |year= 1998 |pmid= 9681824 |doi= 10.1038/sj.onc.1201868 }}
* {{cite journal | vauthors = Wu J, Janknecht R | title = Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A | journal = The Journal of Biological Chemistry | volume = 277 | issue = 45 | pages = 42669–79 | date = Nov 2002 | pmid = 12213813 | doi = 10.1074/jbc.M205501200 }}
*{{cite journal | author=Coutte L, Monté D, Imai K, ''et al.'' |title=Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human. |journal=Oncogene |volume=18 |issue= 46 |pages= 6278-86 |year= 2000 |pmid= 10597226 |doi= 10.1038/sj.onc.1203020 }}
* {{cite journal | vauthors = Janknecht R | title = Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1) | journal = Oncogene | volume = 22 | issue = 5 | pages = 746–55 | date = Feb 2003 | pmid = 12569367 | doi = 10.1038/sj.onc.1206185 }}
*{{cite journal | author=Janknecht R |title=Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 41856-61 |year= 2001 |pmid= 11551945 |doi= 10.1074/jbc.M106630200 }}
* {{cite journal | vauthors = Goel A, Janknecht R | title = Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu | journal = Molecular and Cellular Biology | volume = 23 | issue = 17 | pages = 6243–54 | date = Sep 2003 | pmid = 12917345 | pmc = 180970 | doi = 10.1128/MCB.23.17.6243-6254.2003 }}
*{{cite journal | author=Wu J, Janknecht R |title=Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 42669-79 |year= 2003 |pmid= 12213813 |doi= 10.1074/jbc.M205501200 }}
* {{cite journal | vauthors = Dowdy SC, Mariani A, Janknecht R | title = HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 45 | pages = 44377–84 | date = Nov 2003 | pmid = 12947087 | doi = 10.1074/jbc.M307202200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Goel A, Janknecht R | title = Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu | journal = The Journal of Biological Chemistry | volume = 279 | issue = 15 | pages = 14909–16 | date = Apr 2004 | pmid = 14747462 | doi = 10.1074/jbc.M400036200 }}
*{{cite journal  | author=Janknecht R |title=Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1). |journal=Oncogene |volume=22 |issue= 5 |pages= 746-55 |year= 2003 |pmid= 12569367 |doi= 10.1038/sj.onc.1206185 }}
* {{cite journal | vauthors = Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW | title = Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation | journal = Nature Biotechnology | volume = 22 | issue = 6 | pages = 707–16 | date = Jun 2004 | pmid = 15146197 | doi = 10.1038/nbt971 }}
*{{cite journal | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
* {{cite journal | vauthors = Gocke CB, Yu H, Kang J | title = Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates | journal = The Journal of Biological Chemistry | volume = 280 | issue = 6 | pages = 5004–12 | date = Feb 2005 | pmid = 15561718 | doi = 10.1074/jbc.M411718200 }}
*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal  | author=Goel A, Janknecht R |title=Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu. |journal=Mol. Cell. Biol. |volume=23 |issue= 17 |pages= 6243-54 |year= 2003 |pmid= 12917345 |doi= }}
*{{cite journal | author=Dowdy SC, Mariani A, Janknecht R |title=HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81. |journal=J. Biol. Chem. |volume=278 |issue= 45 |pages= 44377-84 |year= 2004 |pmid= 12947087 |doi= 10.1074/jbc.M307202200 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Goel A, Janknecht R |title=Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu. |journal=J. Biol. Chem. |volume=279 |issue= 15 |pages= 14909-16 |year= 2004 |pmid= 14747462 |doi= 10.1074/jbc.M400036200 }}
*{{cite journal | author=Brandenberger R, Wei H, Zhang S, ''et al.'' |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707-16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gocke CB, Yu H, Kang J |title=Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates. |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 5004-12 |year= 2005 |pmid= 15561718 |doi= 10.1074/jbc.M411718200 }}
}}
{{refend}}
{{refend}}


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* {{MeshName|ETV1+protein,+human}}
* {{MeshName|ETV1+protein,+human}}


 
{{gene-7-stub}}
{{protein-stub}}
{{Transcription factors|g3}}
{{Transcription factors}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}

Latest revision as of 00:38, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

ETS translocation variant 1 is a protein that in humans is encoded by the ETV1 gene.[1][2]

References

  1. ↑ Brown TA, McKnight SL (Dec 1992). "Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins". Genes & Development. 6 (12B): 2502–12. doi:10.1101/gad.6.12b.2502. PMID 1340465.
  2. ↑ "Entrez Gene: ETV1 ets variant gene 1".

Further reading

  • Monté D, Coutte L, Baert JL, Angeli I, Stéhelin D, de Launoit Y (Aug 1995). "Molecular characterization of the ets-related human transcription factor ER81". Oncogene. 11 (4): 771–9. PMID 7651741.
  • Jeon IS, Davis JN, Braun BS, Sublett JE, Roussel MF, Denny CT, Shapiro DN (Mar 1995). "A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1". Oncogene. 10 (6): 1229–34. PMID 7700648.
  • Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  • Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  • Carrère S, Verger A, Flourens A, Stehelin D, Duterque-Coquillaud M (Jun 1998). "Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains". Oncogene. 16 (25): 3261–8. doi:10.1038/sj.onc.1201868. PMID 9681824.
  • Coutte L, Monté D, Imai K, Pouilly L, Dewitte F, Vidaud M, Adamski J, Baert JL, de Launoit Y (Nov 1999). "Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human". Oncogene. 18 (46): 6278–86. doi:10.1038/sj.onc.1203020. PMID 10597226.
  • Janknecht R (Nov 2001). "Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2". The Journal of Biological Chemistry. 276 (45): 41856–61. doi:10.1074/jbc.M106630200. PMID 11551945.
  • Wu J, Janknecht R (Nov 2002). "Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A". The Journal of Biological Chemistry. 277 (45): 42669–79. doi:10.1074/jbc.M205501200. PMID 12213813.
  • Janknecht R (Feb 2003). "Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)". Oncogene. 22 (5): 746–55. doi:10.1038/sj.onc.1206185. PMID 12569367.
  • Goel A, Janknecht R (Sep 2003). "Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu". Molecular and Cellular Biology. 23 (17): 6243–54. doi:10.1128/MCB.23.17.6243-6254.2003. PMC 180970. PMID 12917345.
  • Dowdy SC, Mariani A, Janknecht R (Nov 2003). "HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81". The Journal of Biological Chemistry. 278 (45): 44377–84. doi:10.1074/jbc.M307202200. PMID 12947087.
  • Goel A, Janknecht R (Apr 2004). "Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu". The Journal of Biological Chemistry. 279 (15): 14909–16. doi:10.1074/jbc.M400036200. PMID 14747462.
  • Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (Jun 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
  • Gocke CB, Yu H, Kang J (Feb 2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates". The Journal of Biological Chemistry. 280 (6): 5004–12. doi:10.1074/jbc.M411718200. PMID 15561718.

External links

Retrieved from "https://www.wikidoc.org/index.php?title=ETV1&oldid=1421553"