ELF4: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Underlinked|date=May 2016}}
{{PBB_Controls
{{Infobox_gene}}
| update_page = yes
'''ETS-related transcription factor Elf-4''' is a [[protein]] that in humans is encoded by the ''ELF4'' [[gene]].<ref name="pmid8895518">{{cite journal | vauthors = Miyazaki Y, Sun X, Uchida H, Zhang J, Nimer S | title = MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties | journal = Oncogene | volume = 13 | issue = 8 | pages = 1721–9 |date=Dec 1996 | pmid = 8895518 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2000| accessdate = }}</ref>
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = E74-like factor 4 (ets domain transcription factor)
| HGNCid = 3319
| Symbol = ELF4
| AltSymbols =; ELFR; MEF
| OMIM = 
| ECnumber = 
| Homologene = 31036
| MGIid = 1928377
| GeneAtlas_image1 = PBB_GE_ELF4_31845_at_tn.png
| GeneAtlas_image2 = PBB_GE_ELF4_203490_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0016563 |text = transcription activator activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0016605 |text = PML body}}
| Process = {{GNF_GO|id=GO:0001787 |text = natural killer cell proliferation}} {{GNF_GO|id=GO:0001866 |text = NK T cell proliferation}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2000
    | Hs_Ensembl = ENSG00000102034
    | Hs_RefseqProtein = NP_001412
    | Hs_RefseqmRNA = NM_001421
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 129026530
    | Hs_GenLoc_end = 129072372
    | Hs_Uniprot = Q99607
    | Mm_EntrezGene = 56501
    | Mm_Ensembl = ENSMUSG00000031103
    | Mm_RefseqmRNA = XM_989007
    | Mm_RefseqProtein = XP_994101
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 44657866
    | Mm_GenLoc_end = 44668983
    | Mm_Uniprot = Q32MF0
  }}
}}
'''E74-like factor 4 (ets domain transcription factor)''', also known as '''ELF4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2000| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 56: Line 10:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Liu Y, Hedvat CV, Mao S, ''et al.'' |title=The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2. |journal=Mol. Cell. Biol. |volume=26 |issue= 8 |pages= 3114-23 |year= 2006 |pmid= 16581786 |doi= 10.1128/MCB.26.8.3114-3123.2006 }}
*{{cite journal  | author=Liu Y |title=The ETS Protein MEF Is Regulated by Phosphorylation-Dependent Proteolysis via the Protein-Ubiquitin Ligase SCFSkp2 |journal=Mol. Cell. Biol. |volume=26 |issue= 8 |pages= 3114–23 |year= 2006 |pmid= 16581786 |doi= 10.1128/MCB.26.8.3114-3123.2006 | pmc=1446966  |name-list-format=vanc| author2=Hedvat CV  | author3=Mao S  | display-authors=3  | last4=Zhu  | first4=X.-H.  | last5=Yao  | first5=J.  | last6=Nguyen  | first6=H.  | last7=Koff  | first7=A.  | last8=Nimer  | first8=S. D. }}
*{{cite journal  | author=Moore SD, Offor O, Ferry JA, ''et al.'' |title=ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22). |journal=Leuk. Res. |volume=30 |issue= 8 |pages= 1037-42 |year= 2007 |pmid= 16303180 |doi= 10.1016/j.leukres.2005.10.014 }}
*{{cite journal  | author=Moore SD |title=ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22) |journal=Leuk. Res. |volume=30 |issue= 8 |pages= 1037–42 |year= 2007 |pmid= 16303180 |doi= 10.1016/j.leukres.2005.10.014 |name-list-format=vanc| author2=Offor O  | author3=Ferry JA  | display-authors=3  | last4=Amrein  | first4=P  | last5=Morton  | first5=C  | last6=Dalcin  | first6=P }}
*{{cite journal  | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
*{{cite journal  | author=Ross MT |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286  |name-list-format=vanc| author2=Grafham DV  | author3=Coffey AJ  | display-authors=3  | last4=Scherer  | first4=Steven  | last5=McLay  | first5=Kirsten  | last6=Muzny  | first6=Donna  | last7=Platzer  | first7=Matthias  | last8=Howell  | first8=Gareth R.  | last9=Burrows  | first9=Christine }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Lu Z, Kim KA, Suico MA, ''et al.'' |title=MEF up-regulates human beta-defensin 2 expression in epithelial cells. |journal=FEBS Lett. |volume=561 |issue= 1-3 |pages= 117-21 |year= 2004 |pmid= 15013761 |doi= 10.1016/S0014-5793(04)00138-3 }}
*{{cite journal  | author=Lu Z |title=MEF up-regulates human beta-defensin 2 expression in epithelial cells |journal=FEBS Lett. |volume=561 |issue= 1–3 |pages= 117–21 |year= 2004 |pmid= 15013761 |doi= 10.1016/S0014-5793(04)00138-3 |name-list-format=vanc| author2=Kim KA  | author3=Suico MA  | display-authors=3  | last4=Shuto  | first4=Tsuyoshi  | last5=Li  | first5=Jian-Dong  | last6=Kai  | first6=Hirofumi }}
*{{cite journal  | author=Suico MA, Yoshida H, Seki Y, ''et al.'' |title=Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein. |journal=J. Biol. Chem. |volume=279 |issue= 18 |pages= 19091-8 |year= 2004 |pmid= 14976184 |doi= 10.1074/jbc.M312439200 }}
*{{cite journal  | author=Suico MA |title=Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein |journal=J. Biol. Chem. |volume=279 |issue= 18 |pages= 19091–8 |year= 2004 |pmid= 14976184 |doi= 10.1074/jbc.M312439200 |name-list-format=vanc| author2=Yoshida H  | author3=Seki Y  | display-authors=3  | last4=Uchikawa  | first4=T  | last5=Lu  | first5=Z  | last6=Shuto  | first6=T  | last7=Matsuzaki  | first7=K  | last8=Nakao  | first8=M  | last9=Li  | first9=JD }}
*{{cite journal  | author=Cho JY, Akbarali Y, Zerbini LF, ''et al.'' |title=Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. |journal=J. Biol. Chem. |volume=279 |issue= 19 |pages= 19512-22 |year= 2004 |pmid= 14970218 |doi= 10.1074/jbc.M309074200 }}
*{{cite journal  | author=Cho JY |title=Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene |journal=J. Biol. Chem. |volume=279 |issue= 19 |pages= 19512–22 |year= 2004 |pmid= 14970218 |doi= 10.1074/jbc.M309074200 |name-list-format=vanc| author2=Akbarali Y  | author3=Zerbini LF  | display-authors=3  | last4=Gu  | first4=X  | last5=Boltax  | first5=J  | last6=Wang  | first6=Y  | last7=Oettgen  | first7=P  | last8=Zhang  | first8=DE  | last9=Libermann  | first9=TA }}
*{{cite journal  | author=Hedvat CV, Yao J, Sokolic RA, Nimer SD |title=Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells. |journal=J. Biol. Chem. |volume=279 |issue= 8 |pages= 6395-400 |year= 2004 |pmid= 14625302 |doi= 10.1074/jbc.M307524200 }}
*{{cite journal  | vauthors=Hedvat CV, Yao J, Sokolic RA, Nimer SD |title=Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells |journal=J. Biol. Chem. |volume=279 |issue= 8 |pages= 6395–400 |year= 2004 |pmid= 14625302 |doi= 10.1074/jbc.M307524200 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Suico MA, Koyanagi T, Ise S, ''et al.'' |title=Functional dissection of the ETS transcription factor MEF. |journal=Biochim. Biophys. Acta |volume=1577 |issue= 1 |pages= 113-20 |year= 2002 |pmid= 12151102 |doi=  }}
*{{cite journal  | author=Suico MA |title=Functional dissection of the ETS transcription factor MEF |journal=Biochim. Biophys. Acta |volume=1577 |issue= 1 |pages= 113–20 |year= 2002 |pmid= 12151102 |doi= 10.1016/s0167-4781(02)00370-6|name-list-format=vanc| author2=Koyanagi T  | author3=Ise S  | display-authors=3  | last4=Lu  | first4=Z  | last5=Hisatsune  | first5=A  | last6=Seki  | first6=Y  | last7=Shuto  | first7=T  | last8=Isohama  | first8=Y  | last9=Miyata  | first9=T }}
*{{cite journal  | author=Mao S, Frank RC, Zhang J, ''et al.'' |title=Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias. |journal=Mol. Cell. Biol. |volume=19 |issue= 5 |pages= 3635-44 |year= 1999 |pmid= 10207087 |doi=  }}
*{{cite journal  | author=Mao S |title=Functional and Physical Interactions between AML1 Proteins and an ETS Protein, MEF: Implications for the Pathogenesis of t(8;21)-Positive Leukemias |journal=Mol. Cell. Biol. |volume=19 |issue= 5 |pages= 3635–44 |year= 1999 |pmid= 10207087 |doi= 10.1128/mcb.19.5.3635| pmc=84165  |name-list-format=vanc| author2=Frank RC  | author3=Zhang J  | display-authors=3  | last4=Miyazaki  | first4=Y  | last5=Nimer  | first5=SD }}
*{{cite journal  | author=Aryee DN, Petermann R, Kos K, ''et al.'' |title=Cloning of a novel human ELF-1-related ETS transcription factor, ELFR, its characterization and chromosomal assignment relative to ELF-1. |journal=Gene |volume=210 |issue= 1 |pages= 71-8 |year= 1998 |pmid= 9524226 |doi=  }}
*{{cite journal  | author=Aryee DN |title=Cloning of a novel human ELF-1-related ETS transcription factor, ELFR, its characterization and chromosomal assignment relative to ELF-1 |journal=Gene |volume=210 |issue= 1 |pages= 71–8 |year= 1998 |pmid= 9524226 |doi=10.1016/S0378-1119(98)00022-5 |name-list-format=vanc| author2=Petermann R | author3=Kos K  | display-authors=3  | last4=Henn  | first4=T  | last5=Haas  | first5=O.A  | last6=Kovar  | first6=H }}
*{{cite journal | author=Miyazaki Y, Sun X, Uchida H, ''et al.'' |title=MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties. |journal=Oncogene |volume=13 |issue= 8 |pages= 1721-9 |year= 1996 |pmid= 8895518 |doi=  }}
}}
}}
{{refend}}
{{refend}}
Line 80: Line 34:
* {{MeshName|ELF4+protein,+human}}
* {{MeshName|ELF4+protein,+human}}


{{protein-stub}}
{{Transcription factors|g3}}
{{Transcription factors}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{gene-X-stub}}

Revision as of 00:27, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

ETS-related transcription factor Elf-4 is a protein that in humans is encoded by the ELF4 gene.[1][2]


References

  1. ↑ Miyazaki Y, Sun X, Uchida H, Zhang J, Nimer S (Dec 1996). "MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties". Oncogene. 13 (8): 1721–9. PMID 8895518.
  2. ↑ "Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)".

Further reading

External links


Retrieved from "https://www.wikidoc.org/index.php?title=ELF4&oldid=1423065"