Duodenal atresia natural history, complications and prognosis: Difference between revisions
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{{Duodenal atresia}} | {{Duodenal atresia}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{HQ}} | ||
==Overview== | ==Overview== | ||
The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as [[Bile|bilious]] [[Nausea and vomiting|vomiting]] in 80% of the cases. Prognosis is generally very good, and the survival rate of patients with duodenal atresia is approximately 90%. | |||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
===Natural History=== | ===Natural History=== | ||
*The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as vomiting.<ref name="AdamsStanton2014">{{cite journal|last1=Adams|first1=Stephen D.|last2=Stanton|first2=Michael P.|title=Malrotation and intestinal atresias|journal=Early Human Development|volume=90|issue=12|year=2014|pages=921–925|issn=03783782|doi=10.1016/j.earlhumdev.2014.09.017}}</ref> | *The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as [[Nausea and vomiting|vomiting]].<ref name="AdamsStanton2014">{{cite journal|last1=Adams|first1=Stephen D.|last2=Stanton|first2=Michael P.|title=Malrotation and intestinal atresias|journal=Early Human Development|volume=90|issue=12|year=2014|pages=921–925|issn=03783782|doi=10.1016/j.earlhumdev.2014.09.017}}</ref> | ||
**[[Bile|Bilious]] [[Nausea and vomiting|vomiting]] in 80% of the cases. | |||
**Non-[[Bile|bilious]] [[Nausea and vomiting|vomiting]] in 20% of the cases. | |||
**[[Dehydration]] | |||
*If duodenal atresia is left untreated it will result in death. | |||
===Complications=== | ===Complications=== | ||
*There are no complications associated with duodenal atresia, however post surgical complications may occur. | The complications of duodenal atresia are as follows:<ref name="pmid2273425">{{cite journal| author=Spigland N, Yazbeck S| title=Complications associated with surgical treatment of congenital intrinsic duodenal obstruction. | journal=J Pediatr Surg | year= 1990 | volume= 25 | issue= 11 | pages= 1127-30 | pmid=2273425 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2273425 }} </ref><ref name="pmid3357136">{{cite journal| author=Kokkonen ML, Kalima T, Jääskeläinen J, Louhimo I| title=Duodenal atresia: late follow-up. | journal=J Pediatr Surg | year= 1988 | volume= 23 | issue= 3 | pages= 216-20 | pmid=3357136 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3357136 }} </ref> | ||
*There are no complications associated with duodenal atresia, however post [[Surgery|surgical]] complications may occur. | |||
*Post [[Surgery|surgical]] complications include: | |||
**[[Adhesion (medicine)|Adhesions]] | |||
**[[Duodenum|Duodenal]] dysmotility | |||
**[[Megaduodenum]] with [[blind loop syndrome]] | |||
**Duodenogastric reflux and [[gastritis]] | |||
**[[Peptic ulcer|Peptic ulcer disease]] | |||
**[[Gastroesophageal reflux disease|Gastroesophageal reflux]] | |||
**[[Gallstone disease|Cholelithiasis]] | |||
**[[Chronic cholecystitis|Cholecystitis]] | |||
===Prognosis=== | ===Prognosis=== | ||
*Prognosis is generally good, and the survival rate of patients with duodenal atresia is approximately 90%.<ref name="pmid15185215">{{cite journal| author=Escobar MA, Ladd AP, Grosfeld JL, West KW, Rescorla FJ, Scherer LR et al.| title=Duodenal atresia and stenosis: long-term follow-up over 30 years. | journal=J Pediatr Surg | year= 2004 | volume= 39 | issue= 6 | pages= 867-71; discussion 867-71 | pmid=15185215 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15185215 }} </ref> | *Prognosis is generally good, and the survival rate of patients with duodenal atresia is approximately 90% after surgery.<ref name="pmid15185215">{{cite journal| author=Escobar MA, Ladd AP, Grosfeld JL, West KW, Rescorla FJ, Scherer LR et al.| title=Duodenal atresia and stenosis: long-term follow-up over 30 years. | journal=J Pediatr Surg | year= 2004 | volume= 39 | issue= 6 | pages= 867-71; discussion 867-71 | pmid=15185215 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15185215 }} </ref> | ||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
[[Category: | [[Category:Gastroenterology]] | ||
[[Category:Surgery]] | |||
[[Category:Disease]] | |||
[[Category:Pediatrics]] | |||
[[Category:Up-To-Date]] | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as bilious vomiting in 80% of the cases. Prognosis is generally very good, and the survival rate of patients with duodenal atresia is approximately 90%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of duodenal atresia usually develop in the first 48 hours of life, and start with symptoms such as vomiting.[1]
- Bilious vomiting in 80% of the cases.
- Non-bilious vomiting in 20% of the cases.
- Dehydration
- If duodenal atresia is left untreated it will result in death.
Complications
The complications of duodenal atresia are as follows:[2][3]
- There are no complications associated with duodenal atresia, however post surgical complications may occur.
- Post surgical complications include:
- Adhesions
- Duodenal dysmotility
- Megaduodenum with blind loop syndrome
- Duodenogastric reflux and gastritis
- Peptic ulcer disease
- Gastroesophageal reflux
- Cholelithiasis
- Cholecystitis
Prognosis
- Prognosis is generally good, and the survival rate of patients with duodenal atresia is approximately 90% after surgery.[4]
References
- ↑ Adams, Stephen D.; Stanton, Michael P. (2014). "Malrotation and intestinal atresias". Early Human Development. 90 (12): 921–925. doi:10.1016/j.earlhumdev.2014.09.017. ISSN 0378-3782.
- ↑ Spigland N, Yazbeck S (1990). "Complications associated with surgical treatment of congenital intrinsic duodenal obstruction". J Pediatr Surg. 25 (11): 1127–30. PMID 2273425.
- ↑ Kokkonen ML, Kalima T, Jääskeläinen J, Louhimo I (1988). "Duodenal atresia: late follow-up". J Pediatr Surg. 23 (3): 216–20. PMID 3357136.
- ↑ Escobar MA, Ladd AP, Grosfeld JL, West KW, Rescorla FJ, Scherer LR; et al. (2004). "Duodenal atresia and stenosis: long-term follow-up over 30 years". J Pediatr Surg. 39 (6): 867–71, discussion 867-71. PMID 15185215.