Drug-induced lupus erythematosus (patient information)

For the WikiDoc page for this topic, click here

WikiDoc Resources for Drug-induced lupus erythematosus (patient information)
Articles
Most recent articles on Drug-induced lupus erythematosus (patient information) Most cited articles on Drug-induced lupus erythematosus (patient information) Review articles on Drug-induced lupus erythematosus (patient information) Articles on Drug-induced lupus erythematosus (patient information) in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Drug-induced lupus erythematosus (patient information) Images of Drug-induced lupus erythematosus (patient information) Photos of Drug-induced lupus erythematosus (patient information) Podcasts & MP3s on Drug-induced lupus erythematosus (patient information) Videos on Drug-induced lupus erythematosus (patient information)
Evidence Based Medicine
Cochrane Collaboration on Drug-induced lupus erythematosus (patient information) Bandolier on Drug-induced lupus erythematosus (patient information) TRIP on Drug-induced lupus erythematosus (patient information)
Clinical Trials
Ongoing Trials on Drug-induced lupus erythematosus (patient information) at Clinical Trials.gov Trial results on Drug-induced lupus erythematosus (patient information) Clinical Trials on Drug-induced lupus erythematosus (patient information) at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Drug-induced lupus erythematosus (patient information) NICE Guidance on Drug-induced lupus erythematosus (patient information) NHS PRODIGY Guidance FDA on Drug-induced lupus erythematosus (patient information) CDC on Drug-induced lupus erythematosus (patient information)
Books
Books on Drug-induced lupus erythematosus (patient information)
News
Drug-induced lupus erythematosus (patient information) in the news Be alerted to news on Drug-induced lupus erythematosus (patient information) News trends on Drug-induced lupus erythematosus (patient information)
Commentary
Blogs on Drug-induced lupus erythematosus (patient information)
Definitions
Definitions of Drug-induced lupus erythematosus (patient information)
Patient Resources / Community
Patient resources on Drug-induced lupus erythematosus (patient information) Discussion groups on Drug-induced lupus erythematosus (patient information) Patient Handouts on Drug-induced lupus erythematosus (patient information) Directions to Hospitals Treating Drug-induced lupus erythematosus (patient information) Risk calculators and risk factors for Drug-induced lupus erythematosus (patient information)
Healthcare Provider Resources
Symptoms of Drug-induced lupus erythematosus (patient information) Causes & Risk Factors for Drug-induced lupus erythematosus (patient information) Diagnostic studies for Drug-induced lupus erythematosus (patient information) Treatment of Drug-induced lupus erythematosus (patient information)
Continuing Medical Education (CME)
CME Programs on Drug-induced lupus erythematosus (patient information)
International
Drug-induced lupus erythematosus (patient information) en Espanol Drug-induced lupus erythematosus (patient information) en Francais
Business
Drug-induced lupus erythematosus (patient information) in the Marketplace Patents on Drug-induced lupus erythematosus (patient information)
Experimental / Informatics
List of terms related to Drug-induced lupus erythematosus (patient information)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Jinhui Wu, MD; Ujjwal Rastogi, MBBS [2]

Overview

Drug-induced lupus erythematosus is a side-effect of long-term use of certain medications. The most commom medications that cause drug-induced lupus erythematosus are procainamide, hydralazine and quinidine. Symptoms of drug-induced lupus erythematosus are similar to systemic lupus erythematosus. After stopping the medication that caused the condition, most patients may recover.

What cause drug-induced lupus erythematosus?

Drug-induced lupus erythematosus is caused by a hypersensitivity reaction to a medication. Several following medications are known to cause drug-induced lupus:

• Procainamide
• Hydralazine
• Quinidine
• Chlorpromazine
• Isoniazid
• Methyldopa
• Penicillamine
• Sulfasalazine

What are the symptoms of drug-induced lupus erythematosus?

Symptoms of drug-induced lupus erythematosus always occur after taking the drug for at least 3 to 6 months. Common symptoms are similar to systemic lupus erythemathosus.

• Fatigue and weakness
• Low fever
• Muscle pain
• Joint pain
• Loss of appetite
• Facial butterfly rash
• Sensitivity to sunlight
• Chest pain
• Swollen lymph nodes

Treatment options

Generally, symptoms of drug-induced lupus erythematosus may disappear within several days to weeks after stopping the medication that caused the condition.

• Stop the medications that caused the problem.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs may be used to control inflammation and pain in patients with pain and other symptoms. Usual drugs include ibuprofen, naproxen and indomethacin. Usual side effects are pain, bleeding and ulcers in upper gastrointestinal tract.
• Corticosteroids: Corticosteroids can be used to control many symptoms such as pain and rash. Side effects of corticosteroids may include a decreased ability against infection, worse healing in the wound and osteoporosis.
• Antimalarial drugs: These drugs can be used to treat rash and arthritis in patients with drug-induced lupus erythematosus.

What to expect (Outlook/Prognosis)?

Prognosis of drug-induced lupus erythematosus is better than systemic lupus erythemathosus. Symptoms usually disappear within several days to weeks after stopping the medication that caused the condition.

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000446.htm

See also

• Systemic lupus erythematosus (patient information)

Template:WH Template:WS