Drug-induced lupus erythematosus (patient information)

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Drug-induced lupus erythematosus

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis


When to seek urgent medical care

Treatment options

Where to find medical care for Drug-induced lupus erythematosus ?

What to expect (Outlook/Prognosis)?

Possible complications

Drug-induced lupus erythematosus On the Web

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Jinhui Wu, MD; Ujjwal Rastogi, MBBS [2]

Overview

Drug-induced lupus erythematosus is a side-effect of long-term use of certain medications. The most commom medications that cause drug-induced lupus erythematosus are procainamide, hydralazine and quinidine. Symptoms of drug-induced lupus erythematosus are similar to systemic lupus erythematosus. After stopping the medication that caused the condition, most patients may recover.

What are the symptoms of Drug-induced lupus erythematosus?

Symptoms of drug-induced lupus erythematosus always occur after taking the drug for at least 3 to 6 months. Common symptoms are similar to systemic lupus erythemathosus.

What causes Drug-induced lupus erythematosus?

Drug-induced lupus erythematosus is caused by a hypersensitivity reaction to a medication. Several following medications are known to cause drug-induced lupus:

Who is at highest risk?

The major risk factor for developing drug-induced lupus is chronic, long-term use of a drug known to cause Drug induced lupus.

Diagnosis

The health care provider will listen to your chest with a stethoscope. The doctor may hear a sound called a heart friction rub or pleural friction rub. There may be signs of pericarditis.

A skin exam shows a rash.

Tests that may be done include:

  • Antihistone antibody
  • Antinuclear antibody (ANA) panel
  • Lupus erythematosus cell test (rarely used)

A chest x-ray may show signs of pleuritis or pericarditis. An ECG may show that the heart is affected.

When to seek urgent medical care

Treatment options

Generally, symptoms of drug-induced lupus erythematosus may disappear within several days to weeks after stopping the medication that caused the condition.

Where to find medical care for Drug-induced lupus erythematosus?

Directions to Hospitals Treating Drug-induced lupus erythematosus

What to expect (Outlook/Prognosis)?

Prognosis of drug-induced lupus erythematosus is better than systemic lupus erythemathosus. Symptoms usually disappear within several days to weeks after stopping the medication that caused the condition.

Possible complications

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000446.htm

See also

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