Dextro-transposition of the great arteries corrective surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

Recent advances in surgical correction of transposition of the great arteries have reduced the mortality drastically from 95% in uncorrected patients to 5% in corrected patients[1].

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Immediate post-operative (Jatene procedure) d-TGA + VSD neonate.


Corrective Surgery

Arterial switch operations (ASO) are now-days preferred over Atrial switch procedures (Mustard and Senning Operations) because of the following reasons-

  • Arterial switch procedure are comparatively easier to perform
  • ASO have similar survival benefits compared to atrial switch procedure
  • Decreased risk of complications like arrhythmias and heart failure in ASO compared to atrial switch procedures
  • Decreased peri-operative mortality in ASO compared to atrial switch procedures

Salient features of surgery are

  • It is best to perform the ASO as early as possible in the children. Most infants undergo definitive repair within the first 2 weeks of life.
  • The type of surgical procedure done depends on the type of lesion the child has i.e. simple or complex transposition of the great arteries.
  • The general rules that are followed are-
    • Simple D-TGA (D-TGA without any associated lesion)- Arterial switch operation (ASO).
    • D-TGA plus ventricular septal defect-Arterial switch operation (ASO) and VSD closure.
    • D-TGA plus large VSD plus pulmonary stenosis - Rastelli procedure

Arterial switch or Jatene Operation

Atrial switch repair

Rastelli operation

  • Done for patients with TGA, VSD, and pulmonary outflow tract obstruction.
  • It depends on appropriate VSD anatomy (large and subaortic) because then it will be used as part of the left ventricular outflow tract (LVOT), involving placement of a baffle within the RV to direct blood flow from the VSD to the aorta. A conduit is inserted between the RV and the pulmonary artery, which is stitched.
  • Advantage- Left Ventricle becomes the systemic ventricle
  • Disadvantage- The conduit will likely need to be replaced several times during the patient's life.
  • The appropriate age for this operation is still debated, due to the higher risk with the early repair.
  • The younger the patient the smaller the conduit, needing earlier reoperation.

References

  1. Hutter PA, Kreb DL, Mantel SF, Hitchcock JF, Meijboom EJ, Bennink GB (2002). "Twenty-five years' experience with the arterial switch operation". J Thorac Cardiovasc Surg. 124 (4): 790–7. PMID 12324738.

Acknowledgements and Initial Contributors to Page

Leida Perez, M.D.

External links

nl:Transpositie van de grote vaten

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