Creutzfeldt-Jakob disease physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Physical examination is required for the diagnosis of ‪Creutzfeldt-Jakob disease‬. Physical examination findings of ‪Creutzfeldt-Jakob disease‬findings include uncontrolled sporadic laughter, myoclonus, extrapyramidal signs, akinetic mutism, and visual or cerebellar signs^[1]

Physical Examination

General Appearance

Patients with Creutzfeldt-Jakob disease‬ often appear confused.
Patients often demonstrate uncontrolled sporadic laughter.

Neurologic Examination

Speech impairment
Myoclonus
Ataxia
Gait disturbances
Rigid posture
Dysarthria

References

↑ Rabinovici, GD.; Wang, PN.; Levin, J.; Cook, L.; Pravdin, M.; Davis, J.; DeArmond, SJ.; Barbaro, NM.; Martindale, J. (2006). "First symptom in sporadic Creutzfeldt-Jakob disease". Neurology. 66 (2): 286–7. doi:10.1212/01.wnl.0000196440.00297.67. PMID 16434680. Unknown parameter |month= ignored (help)

[Rabinovici-2006-1] Rabinovici, GD.; Wang, PN.; Levin, J.; Cook, L.; Pravdin, M.; Davis, J.; DeArmond, SJ.; Barbaro, NM.; Martindale, J. (2006). "First symptom in sporadic Creutzfeldt-Jakob disease". Neurology. 66 (2): 286–7. doi:10.1212/01.wnl.0000196440.00297.67. PMID 16434680. Unknown parameter |month= ignored (help)

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