Creutzfeldt-Jakob disease physical examination: Difference between revisions
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==Overview== | ==Overview== | ||
Physical examination is required for the diagnosis of Creutzfeldt-Jakob disease. Physical examination findings of Creutzfeldt-Jakob diseasefindings include [[myoclonus]], [[Neurological examination|extrapyramidal signs]], akinetic mutism, and [[Neurological examination|visual or cerebellar signs]]<ref name="Rabinovici-2006">{{Cite journal | last1 = Rabinovici | first1 = GD. | last2 = Wang | first2 = PN. | last3 = Levin | first3 = J. | last4 = Cook | first4 = L. | last5 = Pravdin | first5 = M. | last6 = Davis | first6 = J. | last7 = DeArmond | first7 = SJ. | last8 = Barbaro | first8 = NM. | last9 = Martindale | first9 = J. | title = First symptom in sporadic Creutzfeldt-Jakob disease. | journal = Neurology | volume = 66 | issue = 2 | pages = 286-7 | month = Jan | year = 2006 | doi = 10.1212/01.wnl.0000196440.00297.67 | PMID = 16434680 }}</ref> | Physical examination is required for the diagnosis of Creutzfeldt-Jakob disease. Physical examination findings of Creutzfeldt-Jakob diseasefindings include uncontrolled sporadic laughter, [[myoclonus]], [[Neurological examination|extrapyramidal signs]], akinetic mutism, and [[Neurological examination|visual or cerebellar signs]]<ref name="Rabinovici-2006">{{Cite journal | last1 = Rabinovici | first1 = GD. | last2 = Wang | first2 = PN. | last3 = Levin | first3 = J. | last4 = Cook | first4 = L. | last5 = Pravdin | first5 = M. | last6 = Davis | first6 = J. | last7 = DeArmond | first7 = SJ. | last8 = Barbaro | first8 = NM. | last9 = Martindale | first9 = J. | title = First symptom in sporadic Creutzfeldt-Jakob disease. | journal = Neurology | volume = 66 | issue = 2 | pages = 286-7 | month = Jan | year = 2006 | doi = 10.1212/01.wnl.0000196440.00297.67 | PMID = 16434680 }}</ref> | ||
==Physical Examination== | ==Physical Examination== | ||
===General Appearance=== | ===General Appearance=== | ||
*Patients with Creutzfeldt-Jakob disease often appear confused. | *Patients with Creutzfeldt-Jakob disease often appear confused. | ||
*Patients often demonstrate uncontrolled sporadic laughter. | |||
===Neurologic Examination=== | ===Neurologic Examination=== | ||
Revision as of 21:13, 22 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Physical examination is required for the diagnosis of Creutzfeldt-Jakob disease. Physical examination findings of Creutzfeldt-Jakob diseasefindings include uncontrolled sporadic laughter, myoclonus, extrapyramidal signs, akinetic mutism, and visual or cerebellar signs[1]
Physical Examination
General Appearance
- Patients with Creutzfeldt-Jakob disease often appear confused.
- Patients often demonstrate uncontrolled sporadic laughter.
Neurologic Examination
- Speech impairment
- Myoclonus
- Ataxia
- Gait disturbances
- Rigid posture
- Dysarthria
References
- ↑ Rabinovici, GD.; Wang, PN.; Levin, J.; Cook, L.; Pravdin, M.; Davis, J.; DeArmond, SJ.; Barbaro, NM.; Martindale, J. (2006). "First symptom in sporadic Creutzfeldt-Jakob disease". Neurology. 66 (2): 286–7. doi:10.1212/01.wnl.0000196440.00297.67. PMID 16434680. Unknown parameter
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