Churg-Strauss syndrome laboratory findings: Difference between revisions

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* C-reactive protein (CRP)  
* C-reactive protein (CRP)  
* Serum troponin<ref name="pmid23853013">{{cite journal| author=McAleavey N, Millar A, Pendleton A| title=Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis. | journal=BMJ Case Rep | year= 2013 | volume= 2013 | issue=  | pages=  | pmid=23853013 | doi=10.1136/bcr-2013-009394 | pmc=3736255 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23853013  }}</ref>  
* Serum troponin<ref name="pmid23853013">{{cite journal| author=McAleavey N, Millar A, Pendleton A| title=Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis. | journal=BMJ Case Rep | year= 2013 | volume= 2013 | issue=  | pages=  | pmid=23853013 | doi=10.1136/bcr-2013-009394 | pmc=3736255 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23853013  }}</ref>  
* Rheumatoid factor 
'''Urinalysis'''  
'''Urinalysis'''  
* Proteinuria
* Proteinuria
* Microscopic hematuria
* Microscopic hematuria
* Albuminuria
* Red blood cell casts
* Red blood cell casts
'''Biopsy'''  
'''Biopsy'''  


Renal biopsy is the
Renal biopsy is the  
 
Diagnostic markers include [[eosinophil granulocyte]]s and [[granuloma]]s in affected tissue and [[Anti-neutrophil cytoplasmic antibody|Anti-neutrophil cytoplasmic antibodies (ANCA)]] against [[neutrophil granulocyte]]s.
 
The findings on other laboratory studies is nonspecific. [[Eosinophilia]] (5K-9K/uL) may be present.  [[Anemia]], elevated [[erythrocyte sedimentation rate]] ([[ESR]]), [[leukocytosis]], elevated [[immunoglobin E]] ([[IgE]]), [[hypergammaglobulinemia]], and a low-positive [[rheumatoid factor]] ([[RF]]





Revision as of 15:56, 14 November 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]

Overview

Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE).

Laboratory Findings

Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophila granulomatosis with polyangiitis are:

Blood Work-up

  • Complete blood count (CBC)
  • Uremia
  • Serum creatinine
  • Blood urea nitrogen (BUN)
  • Antineutrophil cytoplasmic antibody test
  • Eosinophilia
  • Immunoglobulin
  • Erythrocyte sedimentation rate (ESR)
  • C-reactive protein (CRP)
  • Serum troponin[1]
  • Rheumatoid factor

Urinalysis

  • Proteinuria
  • Microscopic hematuria
  • Albuminuria
  • Red blood cell casts

Biopsy

Renal biopsy is the


References

  1. McAleavey N, Millar A, Pendleton A (2013). "Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis". BMJ Case Rep. 2013 ( ):  . doi:10.1136/bcr-2013-009394. PMC 3736255. PMID 23853013.

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