Cholesterol emboli syndrome medical therapy: Difference between revisions

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==Overview==
==Overview==
==Medical Therapy==
==Medical Therapy==
Treatment of an episode of cholesterol emboli is generally symptomatic, i.e. it deals with the symptoms and complications but cannot reverse the phenomenon itself.<ref name=Fukumoto/> In kidney failure resulting from cholesterol crystal emboli, [[statin]]s have been shown to halve the risk of requiring [[hemodialysis]].<ref name=Scolari/>
Treatment of an episode of cholesterol emboli is generally symptomatic, i.e. it deals with the symptoms and complications but cannot reverse the phenomenon itself. In kidney failure resulting from cholesterol crystal emboli, [[statin]]s have been shown to halve the risk of requiring [[hemodialysis]].
* No definitive therapy at this time; supportive care, fluids  
* No definitive therapy at this time; supportive care, fluids  
* The role of anticoagulation is not clear – some of advocated anticoagulation and others have warned against it.
* The role of anticoagulation is not clear – some of advocated anticoagulation and others have warned against it.
Line 10: Line 10:
* Unclear role for glucocorticoids, even when significant eosinophilia is present  
* Unclear role for glucocorticoids, even when significant eosinophilia is present  
*:* Anecdotal case reports have reported improvement
*:* Anecdotal case reports have reported improvement
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 14:27, 27 September 2012

Cholesterol emboli syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Medical Therapy

Treatment of an episode of cholesterol emboli is generally symptomatic, i.e. it deals with the symptoms and complications but cannot reverse the phenomenon itself. In kidney failure resulting from cholesterol crystal emboli, statins have been shown to halve the risk of requiring hemodialysis.

  • No definitive therapy at this time; supportive care, fluids
  • The role of anticoagulation is not clear – some of advocated anticoagulation and others have warned against it.
  • Some have advocated lipid-lowering agents.
  • Unclear role for glucocorticoids, even when significant eosinophilia is present
    • Anecdotal case reports have reported improvement

References


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