Chickenpox screening: Difference between revisions

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==Overview==
==Overview==
Children are vaccinated against chicken pox and most adults generally may have been infected with VZV in their early years. Hence, general population screening is not recommended. But testing for VZV or for the antibodies produced in response to VZV infection may be performed when required.
According to [[Centers for Disease Control and Prevention|Center for Disease Control and Prevention]] ([[Centers for Disease Control and Prevention|CDC]]), there is insufficient evidence to recommend routine [[Screening (medicine)|screening]] among general population. Children are [[Vaccination|vaccinated]] against [[chickenpox]] and most [[Adult|adults]] generally may have been [[Infection (disambiguation)|infected]] with [[Varicella zoster virus|VZV]] in their early years. [[Screening (medicine)|Screening]] is recommended for specific populations which include, healthcare workers, [[pregnant]] women, [[newborns]], [[Human Immunodeficiency Virus (HIV)|HIV]]/[[HIV AIDS|AIDS]] patients and for people prior to [[organ transplantation]].


==Screening==
==Screening==
* Screening is not routinely used to diagnose active cases of chickenpox and [[shingles]]
* According to [[Centers for Disease Control and Prevention|Center for Disease Control and Prevention]] ([[Centers for Disease Control and Prevention|CDC]]), there is insufficient evidence to recommend routine [[Screening (medicine)|screening]] among general population.
* Children are nowadays vaccinated and most adults generally may have been infected with VZV in their early years.Hence, general population screening is not recommended. But, testing for VZV or for the antibodies produced in response to VZV infection may be performed when required.
* Children are [[Vaccination|vaccinated]] and most adults generally may have been [[Infection (disambiguation)|infected]] with [[Varicella zoster virus|VZV]] in their early years. Hence, [[Screening (medicine)|screening]] for general population is not recommended. Testing for [[Varicella zoster virus|VZV]] or for the [[antibodies]] produced in response to [[Varicella-Zoster Virus (VZV) Infections|VZV infection]] may be performed when required.
* Screening tests are recommended for people without symptoms and are at higher risk of acquiring chicken pox.
 
* Blood tests are done to measure the levels of antibodies in the blood which indicates whether the individual has developed an immunity to chickenpox from previous infection or a missed immunization.
=== Screening Varicella in specific populations ===
* Testing for VZV or for the antibodies produced in response to VZV infection may be performed in when required for screening purposes. Also, screening may be advised for newborns, pregnant women, prior to organ transplantation, and in those with HIV/AIDS.
* [[Screening (medicine)|Screening]] tests are recommended for people without [[symptoms]], who are at higher risk of acquiring [[chickenpox]]. The specific groups in which screening for chickenpox is recommended include:<ref name="urlChickenpox and Shingles Tests: The Test">{{cite web |url=https://labtestsonline.org/understanding/analytes/chickenpox/tab/test/ |title=Chickenpox and Shingles Tests: The Test |format= |work= |accessdate=}}</ref>
** Healthcare workers
** Pregnant women
** Newborns
** HIV/AIDS patients
** Potential organ transplant recepients
 
* [[Blood]] tests are done to measure the levels of [[antibodies]] in the [[blood]], which indicates whether the individual has developed an [[Immunity (medical)|immunity]] to [[chickenpox]] from previous [[infection]] or a missed [[immunization]].
* Testing for [[Varicella zoster virus|VZV]] or for the [[antibodies]] produced in response to [[Varicella-Zoster Virus (VZV) Infections|VZV infection]] may be performed for [[Screening (medicine)|screening]] purposes. Also, [[Screening (medicine)|screening]] may be advised for [[newborns]], [[pregnant]] women, prior to [[organ transplantation]], and in those with [[HIV AIDS|HIV/AIDS]].
 
===Antenatal screening===
* Routine [[antenatal]] screening for evidence of [[immunity]] is recommended for [[Pregnancy|pregnant]] women.<ref name="urlPrevention of Varicella: Recommendations of the Advisory Committee on Immunization Practices (ACIP)">{{cite web |url=https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5604a1.htm |title=Prevention of Varicella: Recommendations of the Advisory Committee on Immunization Practices (ACIP) |format= |work= |accessdate=}}</ref>
 
*Routine [[antenatal]] [[Chickenpox|varicella]] [[Screening (medicine)|screening]] of all [[Pregnancy|pregnant]] women with negative or indeterminate [[varicella]] histories is not cost-effective. It could be cost-effective in groups of women with increased exposure risk.<ref name="pmid9540934">{{cite journal |vauthors=Glantz JC, Mushlin AI |title=Cost-effectiveness of routine antenatal varicella screening |journal=Obstet Gynecol |volume=91 |issue=4 |pages=519–28 |year=1998 |pmid=9540934 |doi= |url=}}</ref>
 
===Screening in Healthcare Workers===
*A study shows that 26% to 55% of healthcare workers with no history of [[chickenpox]] and who test negative for [[antibody]] against [[Chickenpox|varicella]] require [[vaccination]]. Hence, in healthcare facilities, [[varicella]] [[Screening (medicine)|screening]] and [[vaccination]] should be offered to all healthcare workers.<ref name="pmid15098642">{{cite journal |vauthors=Chong CY, Lim SH, Ng WY, Tee N, Lin RV |title=Varicella screening and vaccination for healthcare workers at KK Women's and Children's Hospital |journal=Ann. Acad. Med. Singap. |volume=33 |issue=2 |pages=243–7 |year=2004 |pmid=15098642 |doi= |url=}}</ref>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


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Latest revision as of 20:54, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

According to Center for Disease Control and Prevention (CDC), there is insufficient evidence to recommend routine screening among general population. Children are vaccinated against chickenpox and most adults generally may have been infected with VZV in their early years. Screening is recommended for specific populations which include, healthcare workers, pregnant women, newborns, HIV/AIDS patients and for people prior to organ transplantation.

Screening

Screening Varicella in specific populations

  • Screening tests are recommended for people without symptoms, who are at higher risk of acquiring chickenpox. The specific groups in which screening for chickenpox is recommended include:[1]
    • Healthcare workers
    • Pregnant women
    • Newborns
    • HIV/AIDS patients
    • Potential organ transplant recepients

Antenatal screening

Screening in Healthcare Workers

References

  1. "Chickenpox and Shingles Tests: The Test".
  2. "Prevention of Varicella: Recommendations of the Advisory Committee on Immunization Practices (ACIP)".
  3. Glantz JC, Mushlin AI (1998). "Cost-effectiveness of routine antenatal varicella screening". Obstet Gynecol. 91 (4): 519–28. PMID 9540934.
  4. Chong CY, Lim SH, Ng WY, Tee N, Lin RV (2004). "Varicella screening and vaccination for healthcare workers at KK Women's and Children's Hospital". Ann. Acad. Med. Singap. 33 (2): 243–7. PMID 15098642.


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