Cell adhesion molecule 1

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Cell adhesion molecule 1
Identifiers
Symbols CADM1 ; BL2; DKFZp686F1789; IGSF4; IGSF4A; MGC149785; MGC51880; NECL2; Necl-2; RA175; ST17; SYNCAM; TSLC1; sTSLC-1; synCAM1
External IDs Template:OMIM5 Template:MGI HomoloGene8641
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Cell adhesion molecule 1, also known as CADM1, is a human gene.[1]


References

  1. "Entrez Gene: CADM1 cell adhesion molecule 1".

Further reading

  • Watabe K, Ito A, Koma YI, Kitamura Y (2004). "IGSF4: a new intercellular adhesion molecule that is called by three names, TSLC1, SgIGSF and SynCAM, by virtue of its diverse function". Histol. Histopathol. 18 (4): 1321–9. PMID 12973698.
  • Gomyo H, Arai Y, Tanigami A; et al. (2000). "A 2-Mb sequence-ready contig map and a novel immunoglobulin superfamily gene IGSF4 in the LOH region of chromosome 11q23.2". Genomics. 62 (2): 139–46. doi:10.1006/geno.1999.6001. PMID 10610705.
  • Kuramochi M, Fukuhara H, Nobukuni T; et al. (2001). "TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer". Nat. Genet. 27 (4): 427–30. doi:10.1038/86934. PMID 11279526.
  • Masuda M, Yageta M, Fukuhara H; et al. (2002). "The tumor suppressor protein TSLC1 is involved in cell-cell adhesion". J. Biol. Chem. 277 (34): 31014–9. doi:10.1074/jbc.M203620200. PMID 12050160.
  • Fukuhara H, Kuramochi M, Fukami T; et al. (2003). "Promoter methylation of TSLC1 and tumor suppression by its gene product in human prostate cancer". Jpn. J. Cancer Res. 93 (6): 605–9. PMID 12079507.
  • Allinen M, Peri L, Kujala S; et al. (2002). "Analysis of 11q21-24 loss of heterozygosity candidate target genes in breast cancer: indications of TSLC1 promoter hypermethylation". Genes Chromosomes Cancer. 34 (4): 384–9. doi:10.1002/gcc.10079. PMID 12112527.
  • Biederer T, Sara Y, Mozhayeva M; et al. (2002). "SynCAM, a synaptic adhesion molecule that drives synapse assembly". Science. 297 (5586): 1525–31. doi:10.1126/science.1072356. PMID 12202822.
  • Yageta M, Kuramochi M, Masuda M; et al. (2002). "Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer". Cancer Res. 62 (18): 5129–33. PMID 12234973.
  • Jansen M, Fukushima N, Rosty C; et al. (2003). "Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs". Cancer Biol. Ther. 1 (3): 293–6. PMID 12432281.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Honda T, Tamura G, Waki T; et al. (2003). "Hypermethylation of the TSLC1 gene promoter in primary gastric cancers and gastric cancer cell lines". Jpn. J. Cancer Res. 93 (8): 857–60. PMID 12716461.
  • Shingai T, Ikeda W, Kakunaga S; et al. (2003). "Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells". J. Biol. Chem. 278 (37): 35421–7. doi:10.1074/jbc.M305387200. PMID 12826663.
  • Ito A, Okada M, Uchino K; et al. (2003). "Expression of the TSLC1 adhesion molecule in pulmonary epithelium and its down-regulation in pulmonary adenocarcinoma other than bronchioloalveolar carcinoma". Lab. Invest. 83 (8): 1175–83. PMID 12920246.
  • Fukami T, Fukuhara H, Kuramochi M; et al. (2003). "Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines". Int. J. Cancer. 107 (1): 53–9. doi:10.1002/ijc.11348. PMID 12925956.
  • Uchino K, Ito A, Wakayama T; et al. (2003). "Clinical implication and prognostic significance of the tumor suppressor TSLC1 gene detected in adenocarcinoma of the lung". Cancer. 98 (5): 1002–7. doi:10.1002/cncr.11599. PMID 12942568.
  • Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
  • Fukuhara H, Masuda M, Yageta M; et al. (2003). "Association of a lung tumor suppressor TSLC1 with MPP3, a human homologue of Drosophila tumor suppressor Dlg". Oncogene. 22 (40): 6160–5. doi:10.1038/sj.onc.1206744. PMID 13679854.
  • Ito T, Shimada Y, Hashimoto Y; et al. (2003). "Involvement of TSLC1 in progression of esophageal squamous cell carcinoma". Cancer Res. 63 (19): 6320–6. PMID 14559819.
  • Mao X, Seidlitz E, Ghosh K; et al. (2004). "The cytoplasmic domain is critical to the tumor suppressor activity of TSLC1 in non-small cell lung cancer". Cancer Res. 63 (22): 7979–85. PMID 14633730.