Cefuroxime axetil (oral)
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
Overview
Cefuroxime axetil is a second generation oral cephalosporin antibiotic. It was discovered by Glaxo now GlaxoSmithKline and introduced in 1987 asZinnat.[1] It was approved by FDA on Dec 28, 1987.[2] It is available by GSK as Ceftin in US
It is an acetoxyethyl ester prodrug of cefuroxime which is effective orally.The activity depends on in vivo hydrolysis and release of cefuroxime.
Category
Cephalosporins, second generation.
US Brand Names
CEFTIN®
FDA Package Insert
References
http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050605s042lbl.pdf