Cardiac diseases in AIDS natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
[[Pericarditis]] in AIDS is associated with bad prognosis <ref name="pmid10047635">{{cite journal |author=Chen Y, Brennessel D, Walters J, Johnson M, Rosner F, Raza M |title=Human immunodeficiency virus-associated pericardial effusion: report of 40 cases and review of the literature |journal=[[American Heart Journal]] |volume=137 |issue=3 |pages=516–21 |year=1999 |month=March |pmid=10047635 |doi= |url=}}</ref><ref name="pmid7781340">{{cite journal |author=Flum DR, McGinn JT, Tyras DH |title=The role of the 'pericardial window' in AIDS |journal=[[Chest]] |volume=107 |issue=6 |pages=1522–5 |year=1995 |month=June |pmid=7781340 |doi= |url=}}</ref>. Mortality is significantly higher with shortened survival in patients with effusions even if they resolve spontaneously over time <ref name="pmid7586308">{{cite journal |author=Heidenreich PA, Eisenberg MJ, Kee LL, ''et al.'' |title=Pericardial effusion in AIDS. Incidence and survival |journal=[[Circulation]] |volume=92 |issue=11 |pages=3229–34 |year=1995 |month=December |pmid=7586308 |doi= |url=}}</ref>. | Prognosis is very poor in: | ||
* [[Pericarditis]] in AIDS is associated with bad prognosis <ref name="pmid10047635">{{cite journal |author=Chen Y, Brennessel D, Walters J, Johnson M, Rosner F, Raza M |title=Human immunodeficiency virus-associated pericardial effusion: report of 40 cases and review of the literature |journal=[[American Heart Journal]] |volume=137 |issue=3 |pages=516–21 |year=1999 |month=March |pmid=10047635 |doi= |url=}}</ref><ref name="pmid7781340">{{cite journal |author=Flum DR, McGinn JT, Tyras DH |title=The role of the 'pericardial window' in AIDS |journal=[[Chest]] |volume=107 |issue=6 |pages=1522–5 |year=1995 |month=June |pmid=7781340 |doi= |url=}}</ref>. Mortality is significantly higher with shortened survival in patients with effusions even if they resolve spontaneously over time <ref name="pmid7586308">{{cite journal |author=Heidenreich PA, Eisenberg MJ, Kee LL, ''et al.'' |title=Pericardial effusion in AIDS. Incidence and survival |journal=[[Circulation]] |volume=92 |issue=11 |pages=3229–34 |year=1995 |month=December |pmid=7586308 |doi= |url=}}</ref>. | |||
* [[Cardiomyopathy]]: Cardiomyopathy associated with HIV infection carries worst prognosis compared to other non-ischemic types of cardiomyopathy. | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Natural History
The majority of pericardial effusions (80%) in the setting of AIDS were small and asymptomatic. Studies have reported that these effusions resolve spontaneously in 42% of the patients [1].
Complications
Complications from involvement of heart in AIDS include:
- Cardiac tamponade from severe pericardial effusions [2]
- Heart failure from dilated cardiomyopathy (DCM)
- Systemic embolization and stroke from infective endocarditis
- Valvular regurgitations
- Heart blocks
- Superior vena caval syndrome due to cardiac tumors
- Death
Prognosis
Prognosis is very poor in:
- Pericarditis in AIDS is associated with bad prognosis [2][3]. Mortality is significantly higher with shortened survival in patients with effusions even if they resolve spontaneously over time [1].
- Cardiomyopathy: Cardiomyopathy associated with HIV infection carries worst prognosis compared to other non-ischemic types of cardiomyopathy.
References
- ↑ 1.0 1.1 Heidenreich PA, Eisenberg MJ, Kee LL; et al. (1995). "Pericardial effusion in AIDS. Incidence and survival". Circulation. 92 (11): 3229–34. PMID 7586308. Unknown parameter
|month=ignored (help) - ↑ 2.0 2.1 Chen Y, Brennessel D, Walters J, Johnson M, Rosner F, Raza M (1999). "Human immunodeficiency virus-associated pericardial effusion: report of 40 cases and review of the literature". American Heart Journal. 137 (3): 516–21. PMID 10047635. Unknown parameter
|month=ignored (help) - ↑ Flum DR, McGinn JT, Tyras DH (1995). "The role of the 'pericardial window' in AIDS". Chest. 107 (6): 1522–5. PMID 7781340. Unknown parameter
|month=ignored (help)