Carcinoid syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

The prevalence of carcinoid syndrome is approximately 1.5 per 100,000 individuals worldwide. The incidence of carcinoid syndrome is approximately 2 per 100,000 individuals worldwide. The median age at diagnosis is 60.9 years.

Epidemiology and Demographics

Incidence

  • The incidence of carcinoid syndrome is estimated to be 2 cases per 100,000 individuals worldwide.[1]
  • Carcinoid tumors represent about 0.5% of all newly diagnosed malignancies.
  • Carcinoid tumors account for 75% of all gastrointestinal endocrine tumors.
  • Ovarian carcinoid tumors account for 0.3% of all ovarian tumors and 0.5% of carcinoid tumors.[2]

Age

  • Carcinoid syndrome is a disease that tends to affect the elderly population.[3]
  • Ovarian carcinoid tumors are commonly seen in perimenopausal and postmenopausal women.
  • The median age at diagnosis is 60.9 years.[3]

Gender

  • Females are more commonly affected with carcinoid syndrome than males.
  • Males are more commonly affected with thymic carcinoid tumor than females. The male to female ratio is approximately 3 to 1.[4]

Race

Carcinoid syndrome usually affects individuals of the Caucasian race. African American, Latin American, and Asian individuals are less likely to develop carcinoid syndrome.[3]

References

  1. Epidemiology of carcinoid tumor. National cancer institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq
  2. Ovarian carcinoid tumors. Dr Aditya Shetty and Dr Yuranga Weerakkody et al. Radiopaedia 2015. http://radiopaedia.org/articles/ovarian-carcinoid-tumours
  3. 3.0 3.1 3.2 Maggard MA, O'Connell JB, Ko CY (2004). "Updated population-based review of carcinoid tumors". Ann Surg. 240 (1): 117–22. PMC 1356383. PMID 15213627.
  4. Thymic carcinoid tumour. Dr Aditya Shetty and Dr Yuranga Weerakkody et al. Radiopaedia 2015. http://radiopaedia.org/articles/thymic-carcinoid-tumour


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