Brain Stem Gliomas natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
The prognosis of brainstem gliomas depend on: | The prognosis of brainstem gliomas depend on:<ref>Prognosis of brainstem tumors. Cancer gov. http://www.cancer.gov/types/brain/patient/child-glioma-treatment-pdq#link/stoc_h2_2</ref> | ||
*The type of brain stem [[glioma]] | *The type of brain stem [[glioma]] | ||
*Where the tumor is found in the brain and if it has spread within the [[brain stem]] | *Where the tumor is found in the brain and if it has spread within the [[brain stem]] | ||
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As a general rule, dorsal exophytic tumors and cervicomedullary tumors tend to have a good prognosis with treatment, and diffuse type has the worst prognosis with treatment. | As a general rule, dorsal exophytic tumors and cervicomedullary tumors tend to have a good prognosis with treatment, and diffuse type has the worst prognosis with treatment. | ||
<ref>Classification of Brainstem gliomas. Dr Yuranga Weerakkody and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/brainstem-glioma</ref> | |||
*'''''Diffuse brainstem glioma''''' | *'''''Diffuse brainstem glioma''''' | ||
Revision as of 13:54, 27 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Radiotherapy-induced neoplasms tend to be more aggressive in their natural history than their de novo counterparts.
Complications
Morbidity is due to the location of the space-occupying lesion and compression of surrounding structures; because these structures regulate basic body functions of blood pressure, respiration, and swallowing as well as motor and sensory functions, compression can produce substantial neurological disability.
Sudden death can result from increased intracranial pressure and subsequent cerebral herniation. This may be a consequence either of edema induced by the tumor or of hemorrhage into the neoplasm.
Prognosis
The prognosis of brainstem gliomas depend on:[1]
- The type of brain stem glioma
- Where the tumor is found in the brain and if it has spread within the brain stem
- Age of the child when diagnosed
- Whether or not the child has a condition called neurofibromatosis type 1
- Whether the tumor has just been diagnosed or has recurred.
As a general rule, dorsal exophytic tumors and cervicomedullary tumors tend to have a good prognosis with treatment, and diffuse type has the worst prognosis with treatment. [2]
- Diffuse brainstem glioma
- Terrible prognosis
- 90-100% patients die within 2 years of diagnosis
- Focal (tectal glioma)
- Excellent long term survival with CSF shunting (essentially benign lesions)
- Focal (other)
- Good long-term prognosis with surgery
- (Dorsally) exophytic tumors
- Good long-term prognosis with surgery
References
- ↑ Prognosis of brainstem tumors. Cancer gov. http://www.cancer.gov/types/brain/patient/child-glioma-treatment-pdq#link/stoc_h2_2
- ↑ Classification of Brainstem gliomas. Dr Yuranga Weerakkody and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/brainstem-glioma