Blepharitis laboratory findings: Difference between revisions
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However, cultures of the eyelid margins and eyelid biopsy may be indicated for patients who have recurrent anterior blepharitis with severe [[inflammation]], as well as for patients who are not responding to therapy.<ref name="pmid18347619">{{cite journal| author=Jackson WB| title=Blepharitis: current strategies for diagnosis and management. | journal=Can J Ophthalmol | year= 2008 | volume= 43 | issue= 2 | pages= 170-9 | pmid=18347619 | doi=10.1139/i08-016 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18347619 }} </ref><ref name="pmid11009317">{{cite journal| author=McCulley JP, Shine WE| title=Changing concepts in the diagnosis and management of blepharitis. | journal=Cornea | year= 2000 | volume= 19 | issue= 5 | pages= 650-8 | pmid=11009317 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11009317 }} </ref> | However, cultures of the eyelid margins and eyelid biopsy may be indicated for patients who have recurrent anterior blepharitis with severe [[inflammation]], as well as for patients who are not responding to therapy.<ref name="pmid18347619">{{cite journal| author=Jackson WB| title=Blepharitis: current strategies for diagnosis and management. | journal=Can J Ophthalmol | year= 2008 | volume= 43 | issue= 2 | pages= 170-9 | pmid=18347619 | doi=10.1139/i08-016 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18347619 }} </ref><ref name="pmid11009317">{{cite journal| author=McCulley JP, Shine WE| title=Changing concepts in the diagnosis and management of blepharitis. | journal=Cornea | year= 2000 | volume= 19 | issue= 5 | pages= 650-8 | pmid=11009317 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11009317 }} </ref> | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
In general, blepharitis is diagnosed based on clinical features alone. Laboratory studies for blepharitis should include the following:<ref name="pmid18347619">{{cite journal| author=Jackson WB| title=Blepharitis: current strategies for diagnosis and management. | journal=Can J Ophthalmol | year= 2008 | volume= 43 | issue= 2 | pages= 170-9 | pmid=18347619 | doi=10.1139/i08-016 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18347619 }} </ref><ref name="pmid11009317">{{cite journal| author=McCulley JP, Shine WE| title=Changing concepts in the diagnosis and management of blepharitis. | journal=Cornea | year= 2000 | volume= 19 | issue= 5 | pages= 650-8 | pmid=11009317 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11009317 }} </ref><ref name=Blepharitis-1> American Academy of Ophthalmology/ | In general, blepharitis is diagnosed based on clinical features alone. Laboratory studies for blepharitis should include the following:<ref name="pmid18347619">{{cite journal| author=Jackson WB| title=Blepharitis: current strategies for diagnosis and management. | journal=Can J Ophthalmol | year= 2008 | volume= 43 | issue= 2 | pages= 170-9 | pmid=18347619 | doi=10.1139/i08-016 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18347619 }} </ref><ref name="pmid11009317">{{cite journal| author=McCulley JP, Shine WE| title=Changing concepts in the diagnosis and management of blepharitis. | journal=Cornea | year= 2000 | volume= 19 | issue= 5 | pages= 650-8 | pmid=11009317 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11009317 }} </ref><ref name=Blepharitis-1> American Academy of Ophthalmology/Eyewiki (2014) http://eyewiki.aao.org/EyeWiki%3AGeneral_disclaimer| Accessed on July 14, 2016 </ref><ref name="pmid25371637">{{cite journal| author=Bhandari V, Reddy JK| title=Blepharitis: always remember demodex. | journal=Middle East Afr J Ophthalmol | year= 2014 | volume= 21 | issue= 4 | pages= 317-20 | pmid=25371637 | doi=10.4103/0974-9233.142268 | pmc=4219223 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25371637 }} </ref><ref name="pmid21450918">{{cite journal| author=Tomlinson A, Bron AJ, Korb DR, Amano S, Paugh JR, Pearce EI et al.| title=The international workshop on meibomian gland dysfunction: report of the diagnosis subcommittee. | journal=Invest Ophthalmol Vis Sci | year= 2011 | volume= 52 | issue= 4 | pages= 2006-49 | pmid=21450918 | doi=10.1167/iovs.10-6997f | pmc=3072162 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21450918 }} </ref> | ||
#Cultures of the [[eyelid|eyelid margins]] may be indicated for patients who have recurrent anterior blepharitis with severe [[inflammation]], as well as for patients who are not responding to therapy. | #Cultures of the [[eyelid|eyelid margins]] may be indicated for patients who have recurrent anterior blepharitis with severe [[inflammation]], as well as for patients who are not responding to therapy. | ||
#A [[biopsy]] of the eyelid may be indicated to exclude the possibility of [[carcinoma]] in cases of marked [[asymmetry]], [[resistance to therapy]], or unifocal recurrent chalazia that do not respond well to therapy. | #A [[biopsy]] of the eyelid may be indicated to exclude the possibility of [[carcinoma]] in cases of marked [[asymmetry]], [[resistance to therapy]], or unifocal recurrent chalazia that do not respond well to therapy. | ||
Revision as of 14:32, 14 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Overview
Laboratory tests are not often required in patients with Blepharitis. In general, blepharitis is diagnosed based on typical patient history, skin and eye examination, and characteristic slit-lamp biomicroscopic findings. However, cultures of the eyelid margins and eyelid biopsy may be indicated for patients who have recurrent anterior blepharitis with severe inflammation, as well as for patients who are not responding to therapy.[1][2]
Laboratory Findings
In general, blepharitis is diagnosed based on clinical features alone. Laboratory studies for blepharitis should include the following:[1][2][3][4][5]
- Cultures of the eyelid margins may be indicated for patients who have recurrent anterior blepharitis with severe inflammation, as well as for patients who are not responding to therapy.
- A biopsy of the eyelid may be indicated to exclude the possibility of carcinoma in cases of marked asymmetry, resistance to therapy, or unifocal recurrent chalazia that do not respond well to therapy.
- Microscopic evaluation of eyelashes may reveal Demodex mites (indicated for patients who have chronic blepharoconjunctivitis)
References
- ↑ 1.0 1.1 Jackson WB (2008). "Blepharitis: current strategies for diagnosis and management". Can J Ophthalmol. 43 (2): 170–9. doi:10.1139/i08-016. PMID 18347619.
- ↑ 2.0 2.1 McCulley JP, Shine WE (2000). "Changing concepts in the diagnosis and management of blepharitis". Cornea. 19 (5): 650–8. PMID 11009317.
- ↑ American Academy of Ophthalmology/Eyewiki (2014) http://eyewiki.aao.org/EyeWiki%3AGeneral_disclaimer%7C Accessed on July 14, 2016
- ↑ Bhandari V, Reddy JK (2014). "Blepharitis: always remember demodex". Middle East Afr J Ophthalmol. 21 (4): 317–20. doi:10.4103/0974-9233.142268. PMC 4219223. PMID 25371637.
- ↑ Tomlinson A, Bron AJ, Korb DR, Amano S, Paugh JR, Pearce EI; et al. (2011). "The international workshop on meibomian gland dysfunction: report of the diagnosis subcommittee". Invest Ophthalmol Vis Sci. 52 (4): 2006–49. doi:10.1167/iovs.10-6997f. PMC 3072162. PMID 21450918.