Bleeding disorder resident survival guide: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
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== Causes == | == Causes == | ||
The following are the causes of coagulopathy (defects in coagulation): | |||
=== Genetic === | |||
==== Hemorrhagic Disorders ==== | |||
* Factor VIII Deficiency | |||
* Factor IX Deficiency | |||
* Von Willebrand Factor Deficiency | |||
* Factor XI Deficiency | |||
* Factor II, V, VII, X Deficiency (Common Pathway Proteins) | |||
* Factor XIII and Fibrinogen Deficiency | |||
==== Hypercoaguable Diseases ==== | |||
* Antithrombin III Deficiency | |||
* Protein C and S Deficiency | |||
==== Acquired ==== | |||
* Prohemorrhagic Liver Diseases | |||
* Vitamin K Deficiency | |||
* Drugs such as: | |||
** Warfarin | |||
** Heparin | |||
** Hemodilution and massive transfusion | |||
** Disseminated Intravascular Coagulation (DIC) | |||
** Immunoglobulin mediated Factor Deficiency (VIII, V, XIII, X) | |||
** Hyperfibrinolysis | |||
** Venom Induced | |||
==== Prothrombotic ==== | |||
* Heparin Induced Thrombocytopenia | |||
* Antiphospholipid Antibody Syndrome | |||
* Microvascular Thrombosis (Warfarin Induced Skin Necrosis) | |||
== FIRE == | == FIRE == | ||
Revision as of 17:58, 5 December 2018
| Bleeding disorder Resident Survival Guide |
|---|
| Overview |
| Causes |
| FIRE |
| Diagnosis |
| Treatment |
| Do's |
| Don'ts |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];
Overview
Causes
The following are the causes of coagulopathy (defects in coagulation):
Genetic
Hemorrhagic Disorders
- Factor VIII Deficiency
- Factor IX Deficiency
- Von Willebrand Factor Deficiency
- Factor XI Deficiency
- Factor II, V, VII, X Deficiency (Common Pathway Proteins)
- Factor XIII and Fibrinogen Deficiency
Hypercoaguable Diseases
- Antithrombin III Deficiency
- Protein C and S Deficiency
Acquired
- Prohemorrhagic Liver Diseases
- Vitamin K Deficiency
- Drugs such as:
- Warfarin
- Heparin
- Hemodilution and massive transfusion
- Disseminated Intravascular Coagulation (DIC)
- Immunoglobulin mediated Factor Deficiency (VIII, V, XIII, X)
- Hyperfibrinolysis
- Venom Induced
Prothrombotic
- Heparin Induced Thrombocytopenia
- Antiphospholipid Antibody Syndrome
- Microvascular Thrombosis (Warfarin Induced Skin Necrosis)