Bipolar disorder epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Epidemiology and demographics

  • Clinical depression and bipolar disorder are classified as separate illnesses. Some researchers increasingly view them as part of an overlapping spectrum that also includes anxiety and psychosis. The lifetime prevalence of cyclothymic disorder is 0.4-1%. The rate appears equal in men or women, though women more often seek treatment.
  • The estimated lifetime prevalence of bipolar disorder among adults worldwide is 1 to 3 percent[1], and the lifetime prevalence of bipolar I and bipolar II disorder was 2.8 percent[2]
  • The mean age of onset for bipolar I disorder is 18 years and for bipolar II disorder 20 years[3]. The ratio of men to women who develop bipolar disorder is approximately 1:1.
  • In the United States, the estimated lifetime prevalence of bipolar I disorder was 1 percent, and bipolar II disorder 1.1 percent. The mean age of onset for bipolar I and bipolar II disorder was 18 and 20 years.[4]
  • Bipolar disorder is the 18th leading cause of disability in the United States.[5]
  • Individuals with manic or hypomanic episodes, psychosocial functioning is severely impaired in 70 percent; in 90 percent of the affected individuals functioning is severely impaired during episodes of major depression.[4]
  • The one-year prevalence of bipolar I disorder in poeple aged 65 years and older is approximately 0.4 percent and the lifetime rate is 0.8 percent. These rates were less than rates in younger individuals.[6]
  • Geriatric bipolar patients are predominantly female; 69 percent of late-life bipolar patients were women.[7]



References

  1. Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ; et al. (2014). "A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders". JAMA Psychiatry. 71 (5): 573–81. doi:10.1001/jamapsychiatry.2014.16. PMID 24806211. Review in: Evid Based Ment Health. 2015 Feb;18(1):12
  2. Kessler RC, Ormel J, Petukhova M, McLaughlin KA, Green JG, Russo LJ; et al. (2011). "Development of lifetime comorbidity in the World Health Organization world mental health surveys". Arch Gen Psychiatry. 68 (1): 90–100. doi:10.1001/archgenpsychiatry.2010.180. PMC 3057480. PMID 21199968.
  3. Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA; et al. (2011). "Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative". Arch Gen Psychiatry. 68 (3): 241–51. doi:10.1001/archgenpsychiatry.2011.12. PMC 3486639. PMID 21383262.
  4. 4.0 4.1 Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RM, Petukhova M; et al. (2007). "Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication". Arch Gen Psychiatry. 64 (5): 543–52. doi:10.1001/archpsyc.64.5.543. PMC 1931566. PMID 17485606.
  5. Murray CJ, Atkinson C, Bhalla K, Birbeck G, Burstein R, Chou D; et al. (2013). "The state of US health, 1990-2010: burden of diseases, injuries, and risk factors". JAMA. 310 (6): 591–608. doi:10.1001/jama.2013.13805. PMC 5436627. PMID 23842577.
  6. Blanco C, Compton WM, Saha TD, Goldstein BI, Ruan WJ, Huang B | display-authors=etal (2017) Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions - III. J Psychiatr Res 84 ():310-317. DOI:10.1016/j.jpsychires.2016.10.003 PMID: 27814503
  7. Seedat S, Scott KM, Angermeyer MC, Berglund P, Bromet EJ, Brugha TS; et al. (2009). "Cross-national associations between gender and mental disorders in the World Health Organization World Mental Health Surveys". Arch Gen Psychiatry. 66 (7): 785–95. doi:10.1001/archgenpsychiatry.2009.36. PMC 2810067. PMID 19581570.

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