Bedwetting pathophysiology

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Editor(s)-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Steven C. Campbell, M.D., Ph.D., [2] Phone:216-444-5595 Professor of Surgery, Residency Program Director, Section of Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic.

Usual Developmental Process

Most bedwetting can be described as, "a bothersome alteration in normal development." [3] The usual development process is:

• Infants: Void by reflex
• One- and two-year olds: Bladder grows larger and the brain develops the ability to sense bladder fullness (McLorie & Husmann, 1987)
• Two- and three-year olds: Develop the ability to void or inhibit voiding
• Four- and five-year-olds: Develop an adult pattern of urinary control

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