Aspergillus nidulans
| Aspergillus nidulans | ||||||||||||||
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| Aspergillus nidulans G Winter 1884 | ||||||||||||||
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Emericella nidulans |
Aspergillus nidulans (also called Emericella nidulans) is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology [1] for over 50 years, [2] being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, pathogenesis, and metabolism.[3] It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner.
Genome
The genome of A. nidulans, sequenced at the Broad Institute, was published in December 2005. [4] It is 30 million base pairs in size and is predicted to contain around 9,500 protein-coding genes on eight chromosomes.
References
- ↑ Osmani SA, Mirabito PM (2004). "The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans". Fungal Genet Biol. 41 (4): 401–10. PMID 14998523.
- ↑ Martinelli, S. D. (1994). Aspergillus: 50 years on. Elsevier. ISBN 0-444-81762-X. Unknown parameter
|coauthors=ignored (help) - ↑ Nierman WC, May G, Kim HS, Anderson MJ, Chen D, Denning DW (2005). "What the Aspergillus genomes have told us". Med Mycol. 43 Suppl 1: S3–5. PMID 16110785.
- ↑ Galagan JE; et al. (2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 (7071): 1105–15. PMID 16372000.
External links
- Aspergillus nidulans genome [1]
- Fungal Genetics Stock Center