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{{CMG}}; {{AE}} {{Ammu}}
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==Overview==
==Overview==
On biopsy, anaplastic thyroid cancer is characterized by trabecular or solid follicular tumor cells that invade tumor capsule and surrounding vascular structures.
On [[biopsy]], anaplastic thyroid cancer is characterized by [[trabecular]] or solid follicular tumor cells that invade [[tumor capsule]] and surrounding vascular structures.
==Key Biopsy Findings in Anaplastic Thyroid Cancer==
==Key Biopsy Findings in Anaplastic Thyroid Cancer==
During a biopsy, cells are removed from the body so they can be tested in a laboratory. The pathology report from the laboratory will confirm whether or not cancer cells are present in the sample. A biopsy is the only definitive way to diagnose thyroid cancer. The biopsies that could be used for thyroid cancer are:
During a [[biopsy]], cells are removed from the [[body]] so they can be tested in a laboratory. The pathology report from the laboratory will confirm whether or not cancer cells are present in the sample. A [[biopsy]] is the only definitive way to [[diagnose]] thyroid cancer. The biopsies that could be used for thyroid cancer are:
 
===Fine needle aspiration (FNA) biopsy===
Fine needle aspiration (FNA) biopsy
If the nodule isn't big enough to be felt, [[ultrasound]] may be used to guide the needle into the nodule.
If the nodule isn't big enough to be felt, ultrasound may be used to guide the needle into the nodule.
A number of samples may be taken from different areas of the nodule to ensure that the entire [[nodule]] has been examined.
A number of samples may be taken from different areas of the nodule to ensure that the entire nodule has been examined.
If the person has more than one [[nodule]], samples may be taken from each one, depending on the size and appearance of the nodules.
If the person has more than one nodule, samples may be taken from each one, depending on the size and appearance of the nodules.
===Surgical biopsy===
 
* This type of [[biopsy]] may be done if an FNA could not be done
Surgical biopsy
* It was difficult for the pathologist to make a definite [[diagnosis]] from the FNA sample
This type of biopsy may be done if:
* There were multiple nodules in the [[thyroid gland]] and it was too difficult to obtain FNA samples from each of them
an FNA could not be done
* The entire thyroid nodule and possibly the affected lobe of the thyroid will be removed.
the doctor couldn’t obtain enough cells during the FNA for a proper microscopic examination
it was difficult for the pathologist to make a definite diagnosis from the FNA sample
there were multiple nodules in the thyroid gland and it was too difficult to obtain FNA samples from each of them
 
The entire thyroid nodule and possibly the affected lobe of the thyroid will be removed.
==Biopsy Exams of Anaplastic Thyroid Cancer==
==Biopsy Exams of Anaplastic Thyroid Cancer==
[[File:Anaplastic_thyroid_carcinoma_low_mag.jpg|center|Anaplastic thyroid carcinoma with a component of papillary thyroid cancer.]]
[[File:Anaplastic_thyroid_carcinoma_low_mag.jpg|center|Anaplastic thyroid carcinoma with a component of papillary thyroid cancer.]]

Revision as of 18:44, 30 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

On biopsy, anaplastic thyroid cancer is characterized by trabecular or solid follicular tumor cells that invade tumor capsule and surrounding vascular structures.

Key Biopsy Findings in Anaplastic Thyroid Cancer

During a biopsy, cells are removed from the body so they can be tested in a laboratory. The pathology report from the laboratory will confirm whether or not cancer cells are present in the sample. A biopsy is the only definitive way to diagnose thyroid cancer. The biopsies that could be used for thyroid cancer are:

Fine needle aspiration (FNA) biopsy

If the nodule isn't big enough to be felt, ultrasound may be used to guide the needle into the nodule. A number of samples may be taken from different areas of the nodule to ensure that the entire nodule has been examined. If the person has more than one nodule, samples may be taken from each one, depending on the size and appearance of the nodules.

Surgical biopsy

  • This type of biopsy may be done if an FNA could not be done
  • It was difficult for the pathologist to make a definite diagnosis from the FNA sample
  • There were multiple nodules in the thyroid gland and it was too difficult to obtain FNA samples from each of them
  • The entire thyroid nodule and possibly the affected lobe of the thyroid will be removed.

Biopsy Exams of Anaplastic Thyroid Cancer

Anaplastic thyroid carcinoma with a component of papillary thyroid cancer.
Anaplastic thyroid carcinoma with a component of papillary thyroid cancer.

References


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