Adrenal insufficiency physical examination: Difference between revisions

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{{Adrenal insufficiency}}
{{Adrenal insufficiency}}


{{CMG}}; {{AE}}
{{CMG}}; {{AE}} {{Ayeesha}}


==Overview==
==Overview==
Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
Patients with [[adrenal insufficiency]] usually appear [[dehydrated]] and weak. Physical examination of patients with [[primary adrenal insufficiency]] is usually remarkable for hyperpigmentation of skin.
 
OR
 
Common physical examination findings of [disease name] include [finding 1], [finding 2], and [finding 3].
 
OR
 
The presence of [finding(s)] on physical examination is diagnostic of [disease name].
 
OR
 
The presence of [finding(s)] on physical examination is highly suggestive of [disease name].


==Physical Examination==
==Physical Examination==
Physical examination of patients with [disease name] is usually normal.
Physical examination of patients with [[primary adrenal insufficiency]] is usually remarkable for hyperpigmentation of skin. <ref name="LeeCho2017">{{cite journal|last1=Lee|first1=Ye Yeon|last2=Cho|first2=Nan Hee|last3=Lee|first3=Jong Won|last4=Kim|first4=Nam Kyung|last5=Kim|first5=Hye Soon|last6=Kim|first6=Mi-Kyung|title=Clinical Characteristics of Patients with Adrenal Insufficiency in a General Hospital|journal=Endocrinology and Metabolism|volume=32|issue=1|year=2017|pages=83|issn=2093-596X|doi=10.3803/EnM.2017.32.1.83}}</ref>
 
OR
 
Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
 
OR
 
The presence of [finding(s)] on physical examination is diagnostic of [disease name].
 
OR
 
The presence of [finding(s)] on physical examination is highly suggestive of [disease name].


===Appearance of the Patient===
===Appearance of the Patient===
*Patients with [disease name] usually appear [general appearance].  
*Patients with [[adrenal insufficiency]] usually appear [[dehydrated]] or weak.


===Vital Signs===
===Vital Signs===
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*Loss of axillary and pubic hair in women with [[primary adrenal insufficiency]]
*Loss of axillary and pubic hair in women with [[primary adrenal insufficiency]]
*Horizontal bands of [[hyperpigmentation]] on the nails.
*Horizontal bands of [[hyperpigmentation]] on the nails.
Following image shows mucosal hyperpigmentation in Addison's disease:
[[Image:Addisons hyperpigmentation.jpg|thumb|center|500px|Mucosal hyperpigmentation - By FlatOut - Dermatology Online Journal http://dermatology.cdlib.org/, CC0, https://commons.wikimedia.org/w/index.php?curid=25847348]]


===HEENT===
===HEENT===
Line 60: Line 40:


===Heart===
===Heart===
* Cardiovascular examination of patients with [disease name] is usually normal.
* Cardiovascular examination of patients with [[adrenal insufficiency]] is usually normal.
OR
*Chest tenderness upon palpation
*PMI within 2 cm of the sternum  (PMI) / Displaced point of maximal impulse (PMI) suggestive of ____
*[[Heave]] / [[thrill]]
*[[Friction rub]]
*[[Heart sounds#First heart tone S1, the "lub"(components M1 and T1)|S1]]
*[[Heart sounds#Second heart tone S2 the "dub"(components A2 and P2)|S2]]
*[[Heart sounds#Third heart sound S3|S3]]
*[[Heart sounds#Fourth heart sound S4|S4]]
*[[Heart sounds#Summation Gallop|Gallops]]
*A high/low grade early/late [[systolic murmur]] / [[diastolic murmur]] best heard at the base/apex/(specific valve region) may be heard using the bell/diaphgram of the stethoscope


===Abdomen===
===Abdomen===
* Abdominal examination of patients with [disease name] is usually normal.
*[[Abdominal tenderness]] and [[guarding]] can be present in [[adrenal crisis]] <ref>https://www.amjmed.com/article/S0002-9343(15)00827-X/pdf</ref>
OR
*[[Abdominal distension]]  
*[[Abdominal tenderness]] in the right/left upper/lower abdominal quadrant
*[[Rebound tenderness]] (positive Blumberg sign)
*A palpable abdominal mass in the right/left upper/lower abdominal quadrant
*Guarding may be present
*[[Hepatomegaly]] / [[splenomegaly]] / [[hepatosplenomegaly]]
*Additional findings, such as obturator test, psoas test, McBurney point test, Murphy test


===Back===
===Back===
* Back examination of patients with [disease name] is usually normal.
* Back examination of patients with [[adrenal insufficiency]] is usually normal.
OR
*Point tenderness over __ vertebrae (e.g. L3-L4)
*Sacral edema
*Costovertebral angle tenderness bilaterally/unilaterally
*Buffalo hump


===Genitourinary===
===Genitourinary===
* Genitourinary examination of patients with [disease name] is usually normal.
* Genitourinary examination of patients with [[adrenal insufficiency]] is usually normal.
OR
*A pelvic/adnexal mass may be palpated
*Inflamed mucosa
*Clear/(color), foul-smelling/odorless penile/vaginal discharge


===Neuromuscular===
===Neuromuscular===
* Neuromuscular examination of patients with [disease name] is usually normal.
* Altered mental status maybe seen in patients with [[adrenal crisis]] <ref>https://www.amjmed.com/article/S0002-9343(15)00827-X/pdf</ref>
OR
*Patient is usually oriented to persons, place, and time
* Altered mental status
* Glasgow coma scale is ___ / 15
* Clonus may be present
* Hyperreflexia / hyporeflexia / areflexia
* Positive (abnormal) Babinski / plantar reflex unilaterally/bilaterally
* Muscle rigidity
* Proximal/distal muscle weakness unilaterally/bilaterally
* ____ (finding) suggestive of cranial nerve ___ (roman numerical) deficit (e.g. Dilated pupils suggestive of CN III deficit)
*Unilateral/bilateral upper/lower extremity weakness
*Unilateral/bilateral sensory loss in the upper/lower extremity
*Positive straight leg raise test
*Abnormal gait (describe gait: e.g. ataxic (cerebellar) gait / steppage gait / waddling gait / choeiform gait / Parkinsonian gait / sensory gait)
*Positive/negative Trendelenburg sign
*Unilateral/bilateral tremor (describe tremor, e.g. at rest, pill-rolling)
*Normal finger-to-nose test / Dysmetria
*Absent/present dysdiadochokinesia (palm tapping test)


===Extremities===
===Extremities===
* Extremities examination of patients with [disease name] is usually normal.
* Extremities examination of patients with [[adrenal insufficiency]] is usually normal.
OR
*[[Clubbing]]
*[[Cyanosis]]
*Pitting/non-pitting [[edema]] of the upper/lower extremities
*Muscle atrophy
*Fasciculations in the upper/lower extremity


==References==
==References==

Latest revision as of 18:13, 7 December 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayeesha Kattubadi, M.B.B.S[2]

Overview

Patients with adrenal insufficiency usually appear dehydrated and weak. Physical examination of patients with primary adrenal insufficiency is usually remarkable for hyperpigmentation of skin.

Physical Examination

Physical examination of patients with primary adrenal insufficiency is usually remarkable for hyperpigmentation of skin. [1]

Appearance of the Patient

Vital Signs

Skin

Following image shows mucosal hyperpigmentation in Addison's disease:

Mucosal hyperpigmentation - By FlatOut - Dermatology Online Journal http://dermatology.cdlib.org/, CC0, https://commons.wikimedia.org/w/index.php?curid=25847348

HEENT

Neck

Lungs

Heart

Abdomen

Back

Genitourinary

Neuromuscular

Extremities

References

  1. Lee, Ye Yeon; Cho, Nan Hee; Lee, Jong Won; Kim, Nam Kyung; Kim, Hye Soon; Kim, Mi-Kyung (2017). "Clinical Characteristics of Patients with Adrenal Insufficiency in a General Hospital". Endocrinology and Metabolism. 32 (1): 83. doi:10.3803/EnM.2017.32.1.83. ISSN 2093-596X.
  2. "StatPearls". 2020. PMID 28722862.
  3. Pazderska, Agnieszka; Pearce, Simon HS (2017). "Adrenal insufficiency – recognition and management". Clinical Medicine. 17 (3): 258–262. doi:10.7861/clinmedicine.17-3-258. ISSN 1470-2118.
  4. Lause M, Kamboj A, Fernandez Faith E (2017). "Dermatologic manifestations of endocrine disorders". Transl Pediatr. 6 (4): 300–312. doi:10.21037/tp.2017.09.08. PMC 5682371. PMID 29184811.
  5. Sarkar, SoumyaBrata; Sarkar, Subrata; Ghosh, Supratim; Bandyopadhyay, Subhankar (2012). "Addison′s disease". Contemporary Clinical Dentistry. 3 (4): 484. doi:10.4103/0976-237X.107450. ISSN 0976-237X.
  6. https://www.amjmed.com/article/S0002-9343(15)00827-X/pdf
  7. https://www.amjmed.com/article/S0002-9343(15)00827-X/pdf

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