Additional sex combs like 2, transcriptional regulator

Revision as of 19:01, 29 August 2017 by en>KolbertBot (Bot: HTTP→HTTPS)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Additional sex combs like 2, transcriptional regulator is a protein that in humans is encoded by the ASXL2 gene. [1]

Function

This gene encodes a member of a family of epigenetic regulators that bind various histone-modifying enzymes and are involved in the assembly of transcription factors at specific genomic loci. Naturally occurring mutations in this gene are associated with cancer in several tissue types (breast, bladder, pancreas, ovary, prostate, and blood). This gene plays an important role in neurodevelopment, cardiac function, adipogenesis, and osteoclastogenesis.

References

  1. "Entrez Gene: Additional sex combs like 2, transcriptional regulator". Retrieved 2017-06-03.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.