Acute promyelocytic leukemia epidemiology and demographics: Difference between revisions

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==Epidemiology and Demographics==
==Epidemiology and Demographics==
Acute promyelocytic leukemia represents 10-15%% of all cases of acute myeloid leukemia in adults.<ref name="pmid29541170">{{cite journal| author=Chen C, Huang X, Wang K, Chen K, Gao D, Qian S| title=Early mortality in acute promyelocytic leukemia: Potential predictors. | journal=Oncol Lett | year= 2018 | volume= 15 | issue= 4 | pages= 4061-4069 | pmid=29541170 | doi=10.3892/ol.2018.7854 | pmc=5835847 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29541170  }} </ref> The median age is approximately 40 years, which is considerably younger than the other subtypes of acute myeloid leukemia (70 years). The incidence is increased in patients originated in Latin American countries.  
*The incidence of acute promyelocytic leukemia is 0.2 to 0.26 per 100,000 annually in the United States, which corresponds to 600-800 cases of acute promyelocytic leukemia per year.<ref name="pmid22707337">{{cite journal| author=Chen Y, Kantarjian H, Wang H, Cortes J, Ravandi F| title=Acute promyelocytic leukemia: a population-based study on incidence and survival in the United States, 1975-2008. | journal=Cancer | year= 2012 | volume= 118 | issue= 23 | pages= 5811-8 | pmid=22707337 | doi=10.1002/cncr.27623 | pmc=4180246 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22707337  }} </ref>
*The incidence is higher in people of Latin American descent compared to Caucasian descent.
*Acute promyelocytic leukemia represents 10-15%% of all cases of acute myeloid leukemia in adults.<ref name="pmid29541170">{{cite journal| author=Chen C, Huang X, Wang K, Chen K, Gao D, Qian S| title=Early mortality in acute promyelocytic leukemia: Potential predictors. | journal=Oncol Lett | year= 2018 | volume= 15 | issue= 4 | pages= 4061-4069 | pmid=29541170 | doi=10.3892/ol.2018.7854 | pmc=5835847 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29541170  }} </ref> The median age is approximately 40 years, which is considerably younger than the other subtypes of acute myeloid leukemia (70 years).  


==References==
==References==

Revision as of 06:27, 13 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]

Epidemiology and Demographics

  • The incidence of acute promyelocytic leukemia is 0.2 to 0.26 per 100,000 annually in the United States, which corresponds to 600-800 cases of acute promyelocytic leukemia per year.[1]
  • The incidence is higher in people of Latin American descent compared to Caucasian descent.
  • Acute promyelocytic leukemia represents 10-15%% of all cases of acute myeloid leukemia in adults.[2] The median age is approximately 40 years, which is considerably younger than the other subtypes of acute myeloid leukemia (70 years).

References

  1. Chen Y, Kantarjian H, Wang H, Cortes J, Ravandi F (2012). "Acute promyelocytic leukemia: a population-based study on incidence and survival in the United States, 1975-2008". Cancer. 118 (23): 5811–8. doi:10.1002/cncr.27623. PMC 4180246. PMID 22707337.
  2. Chen C, Huang X, Wang K, Chen K, Gao D, Qian S (2018). "Early mortality in acute promyelocytic leukemia: Potential predictors". Oncol Lett. 15 (4): 4061–4069. doi:10.3892/ol.2018.7854. PMC 5835847. PMID 29541170.

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