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| __NOTOC__ | | __NOTOC__ |
| | {{Acute disseminated encephalomyelitis}} |
| | {{CMG}}; {{AE}} {{Sujaya}} {{SHM}} |
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| {{CMG}}; {{AE}}
| | '''''Synonyms and Keywords:''''' post infectious [[encephalomyelitis]]; [[Autoimmune]] [[demyelinating disease]] of [[central nervous system]] |
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| '''''Synonyms and Keywords:''''' post infectious encephalomyelitis; Autoimmune demyelinating disease of central nervous system
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| {{Infobox_Disease |
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| Name = {{PAGENAME}} |
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| Image = |
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| Caption = |
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| DiseasesDB = 158 |
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| ICD10 = {{ICD10|G|04|0|g|00}} |
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| ICD9 = {{ICD9|323.61}} |
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| ICDO = |
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| OMIM = |
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| MedlinePlus = |
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| MeshID = D004673 |
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| }}
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| ==[[Acute disseminated encephalomyelitis overview|Overview]]== | | ==[[Acute disseminated encephalomyelitis overview|Overview]]== |
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| ==[[Acute disseminated encephalomyelitis historical perspective|Historical Perspective]]== | | ==[[Acute disseminated encephalomyelitis historical perspective|Historical Perspective]]== |
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| ===Discovery===
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| *There is limited information about the historical perspective of [disease name].
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| *[Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
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| *The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
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| *In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
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| *In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
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| ===Landmark Events in the Development of Treatment Strategies===
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| ===Impact on Cultural History===
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| ===Famous Cases===
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| The following are a few famous cases of [disease name]:
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| ==[[Acute disseminated encephalomyelitis classification|Classification]]== | | ==[[Acute disseminated encephalomyelitis classification|Classification]]== |
| There is no established system for the classification of [disease name].
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| [Disease name] may be classified according to [classification method] into [number] subtypes/groups:
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| *[Group1]
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| *[Group2]
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| *[Group3]
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| *[Group4]
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| OR
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| [Disease name] may be classified into [large number > 6] subtypes based on:
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| *[Classification method 1]
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| *[Classification method 2]
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| *[Classification method 3]
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| [Disease name] may be classified into several subtypes based on:
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| *[Classification method 1]
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| *[Classification method 2]
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| *[Classification method 3]
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| Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
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| '''If the staging system involves specific and characteristic findings and features:'''
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| According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
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| The staging of [malignancy name] is based on the [staging system].
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| There is no established system for the staging of [malignancy name].
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| ==[[Acute disseminated encephalomyelitis pathophysiology|Pathophysiology]]== | | ==[[Acute disseminated encephalomyelitis pathophysiology|Pathophysiology]]== |
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| ==Overview==
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| The exact pathogenesis of [disease name] is not fully understood.
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| It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
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| [Pathogen name] is usually transmitted via the [transmission route] route to the human host.
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| Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
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| OR
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| [Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
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| The progression to [disease name] usually involves the [molecular pathway].
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| The pathophysiology of [disease/malignancy] depends on the histological subtype.
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| The actual mechanism of ADEM is unknown, however it is assumed to be caused by inflammation in genetically predisposed individuals provoked by an environmental stimulation (e.g., immunization or viral illness).
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| <br />
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| ==Pathophysiology==
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| ===Physiology===
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| The normal physiology of [name of process] can be understood as follows:
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| ===Pathogenesis===
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| *The exact pathogenesis of [disease name] is not completely understood.
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| OR
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| *It is understood that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
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| *[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
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| *Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
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| *[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
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| *The progression to [disease name] usually involves the [molecular pathway].
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| *The pathophysiology of [disease/malignancy] depends on the histological subtype.
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| ==[[Acute disseminated encephalomyelitis causes|Causes]]== | | ==[[Acute disseminated encephalomyelitis causes|Causes]]== |
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| == Overview ==
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| Disease name] may be caused by [cause1], [cause2], or [cause3].
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| Common causes of [disease] include [cause1], [cause2], and [cause3].
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| The most common cause of [disease name] is [cause 1]. Less common causes of [disease name] include [cause 2], [cause 3], and [cause 4].
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| OR
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| The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click here.
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| ==Causes==
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| *Symptom/manifestation] include [cause1], [cause2], and [cause3].
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| *[Cause] is a life-threatening cause of [disease].
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| ===Common Causes===
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| Common causes of [disease name] may include:
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| *[Cause1]
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| *[Cause2]
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| *[Cause3]
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| ==[[Acute disseminated encephalomyelitis differential diagnosis|Differentiating Acute disseminated encephalomyelitis from other Diseases]]== | | ==[[Acute disseminated encephalomyelitis differential diagnosis|Differentiating Acute disseminated encephalomyelitis from other Diseases]]== |
| Overview
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| [Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
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| [Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].
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| Differentiating [Disease name] from other Diseases
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| [Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
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| OR
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| [Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
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| As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
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| Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]
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| On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].
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| ==[[Acute disseminated encephalomyelitis epidemiology and demographics|Epidemiology and Demographics]]== | | ==[[Acute disseminated encephalomyelitis epidemiology and demographics|Epidemiology and Demographics]]== |
| | [[Category: (name of the system)]] |
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| ==[[Acute disseminated encephalomyelitis risk factors|Risk Factors]]== | | ==[[Acute disseminated encephalomyelitis risk factors|Risk Factors]]== |
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| ==Case Studies== | | ==Case Studies== |
| [[Acute disseminated encephalomyelitis case study one|Case #1]] | | [[Acute disseminated encephalomyelitis case study one|Case #1]] |
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| ==Acknowledgements==
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| The content on this page was first contributed by: ELLISON L. SMITH, M.D.
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| ==Related Chapters== | | ==Related Chapters== |