Abdelrahman Ibrahim Abushouk

Abdelrahman I. Abushouk, MD I Email: Aabushou@bidmc.harvard.edu

Education

• Bachelor of Medicine and Surgery (MBBCh), Faculty of Medicine, Ain Shams University, Cairo, Egypt. I officially graduated with Excellence with Honors in June 2016 (Among top Class Graduates; Summa Cum Laude).

Current Position

• Postdoctoral Research Fellow at PERFUSE Study Group, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
• Associate Editor-in-Chief at WikiDoc Foundation (WikiDoc.org)
• Guest Executive Editor, Current Pharmaceutical Design, Bentham Science Publishers, UAE
• Review Editor, Frontiers in Cardiovascular Medicine (Cardio-Oncology Section), Frontiers Publishers, Switzerland.

Research Impact

• My research has shown the value of iFR and MD-CT in the assessment of challenging coronary lesions (bifurcation and chronic total occlusion).
• Our research established the non-inferiority of TAVR to SAVR in low-to-moderate risk patients with aortic stenosis and compared the outcomes of different valves.
• In cardio-oncology, we assessed the burden of cardiac tumors and cancer-related cardiac death.
• Through basic research, we uncovered the value of some therapeutics as diosmin, metformin, and telmisartan in preventing chemotherapy-induced cardiotoxicity.
• Research cited in 12 national/international guidelines, drug updates, and state policies.
• Overall, my research was cited about 800 times according to Google Scholar and 600 times according to Scopus Database (h-index: 13-16).
• More than 30 papers listed by the NICE Guidelines website as reliable sources of evidence.
• Research covered in Scientific American and Atlas of Science magazine.

Awards, Grants, and Scholarships

1. Nominee for Fulbright Award 2018 - Binational Fulbright Commission in Egypt, Cairo, Egypt
2. Research Support Grant - Deanship of Scientific Research, King Faisal University, SA (Grant No. 160021)
3. Research Support Grant - Deanship of Scientific Research, King Saud University, SA (Grant No. RGP-018)
4. Excellence and Scholastic Outstanding Achievement Award (For ranking among the top students in my Bachelor Degree Class), Ain Shams University, Cairo, Egypt (March 2016).
5. Publons Peer Review Awards (Publons – Clarivate Analytics^®): In 2018 and 2019 in the fields of Clinical Medicine (Global rank: 2) and Biochemistry and Molecular Biology (Global rank: 22).
6. Best Poster Presentation Award - American College of Cardiology Conference (Sep, 2017, Riyadh, KSA); 5000 USD and the abstract is published under the Best Posters Section of JACC.
7. Young Investigator Award - 11^th World Stroke Congress 2018, World Stroke Federation (Montreal, Canada). The abstract is now published in the International Journal of Stroke.
8. IBRO Full Scholarships (travel, accommodation and training) on immunohistochemistry and confocal microscopy (Cape Town University, SA & Mohamed V University, Morocco).

Peer-reviewed Publications

1. Gamal AS, Akleh S, Zaman A, Das R, Abushouk AI, Edwards R. Outcomes of Direct Flow Medical vs Sapien 3 Transcatheter Aortic Valve Devices. J Cardiovasc Transl Res. 2019 Dec 17. PMID: 31848880.
2. AlKahtane AA, Abushouk AI, Mohammed ET, ALNasser M, Alarifi S, Ali D, Alessia MS, Almeer RS, AlBasher G, Alkahtani S, Aleya L, Abdel-Daim MM. Fucoidan alleviates microcystin-LR-induced hepatic, renal, and cardiac oxidative stress and inflammatory injuries in mice. Environ Sci Pollut Res Int. 2019 Dec 14. PMID: 31838672.
3. Radi AM, Mohammed ET, Abushouk AI, Aleya L, Abdel-Daim MM. The effects of abamectin on oxidative stress and gene expression in rat liver and brain tissues: Modulation by sesame oil and ascorbic acid. Sci Total Environ. 2020 Jan 20; 701:134882. PMID: 31739238.
4. Gad MM, Saad AM, Al-Husseini MJ, Abushouk AI, Salahia S, Rehman KA, Riaz H, Ahmed HM. Temporal trends, ethnic determinants, and short-term and long-term risk of cardiac death in cancer patients: a cohort study. Cardiovasc Pathol. 2019 Nov - Dec; 43:107147. PMID: 31494524.
5. Abushouk AI, Salem AMA, Saad A, Afifi AM, Afify AY, Afify H, Salem HSE, Ghanem E, Abdel-Daim MM. Mesenchymal Stem Cell Therapy for Doxorubicin-Induced Cardiomyopathy: Potential Mechanisms, Governing Factors, and Implications of the Heart Stem Cell Debate. Front Pharmacol. 2019; 10:635. PMID: 31258475.
6. Abdel-Daim MM, Abushouk AI, Donia T, Alarifi S, Alkahtani S, Aleya L, Bungau SG. The nephroprotective effects of allicin and ascorbic acid against cisplatin-induced toxicity in rats. Environ Sci Pollut Res Int. 2019 May; 26(13):13502-13509. PMID: 30911969.
7. Montasser MF, Zaky S, Salaheldin M, Johar D, Abushouk AI, El-Raey F, Al-Husseini M, Mohammed EG. Fib-4 Predicts Early Hematological Adverse Events Induced by Interferon-Based Triple Therapy in Chronic Hepatitis C Virus Patients. J Interferon Cytokine Res. 2019 02; 39(2):85-94. PMID: 30657408.
8. Ibrahim A, Al-Hizab FA, Abushouk AI, Abdel-Daim MM. Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation. Front Pharmacol. 2018; 9:1268. PMID: 30524274.
9. Al-Husseini MJ, Mohamed HH, Saad AM, Gad MM, Atia M, Qaddoora U, Abushouk AI, El-Shinawi M. Risk and survival of chronic myeloid leukemia after breast cancer: A population-based study. Curr Probl Cancer. 2019 Jun; 43(3):213-221. PMID: 30195804.
10. Abdel-Daim MM, Abushouk AI, Alkhalf MI, Toraih EA, Fawzy MS, Ijaz H, Aleya L, Bungau SG. Antagonistic effects of Spirulina platensis on diazinon-induced hemato-biochemical alterations and oxidative stress in rats. Environ Sci Pollut Res Int. 2018 Sep; 25(27):27463-27470. PMID: 30043347.
11. Ghanem E, Elgazar M, Oweda K, Tarek H, Assaf F, Ahmed El-Husseny MW, Elgebaly A, Abushouk AI. Awareness of Basic Life Support among Egyptian Medical Students; a Cross-Sectional Study. Emerg (Tehran). 2018; 6(1):e36. PMID: 30009238.
12. Abdelmoneim I, Sadek A, Mosaad MA, Yassin I, Radwan Y, Shokry K, Magdy A, Elsherbeny MY, Abushouk AI. Diagnostic accuracy of multi-slice computed tomography in identifying lesion characteristics in coronary total occlusion. Int J Cardiovasc Imaging. 2018 Nov; 34(11):1813-1818. PMID: 29948635.
13. Abdel-Daim MM, Shaheen HM, Abushouk AI, Toraih EA, Fawzy MS, Alansari WS, Aleya L, Bungau S. Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats. Environ Sci Pollut Res Int. 2018 Aug; 25(24):23909-23916. PMID: 29881965.
14. Fouda S, Kelany M, Moustafa N, Abushouk AI, Hassane A, Sleem A, Mokhtar O, Negida A, Bassiony M. Tobacco smoking in Egypt: a scoping literature review of its epidemiology and control measures. East Mediterr Health J. 2018 May 03; 24(2):198-215. PMID: 29748949.
15. Shaheen M, Mokarrab M, Youssef A, Aref M, Abushouk AI, Elmaraezy A, Almasswary A. Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using instantaneous wave-free ratio. Indian Heart J. 2018 Dec; 70 Suppl 3:S254-S258. PMID: 30595269.
16. Baratloo A, Rahimpour L, Abushouk AI, Safari S, Lee CW, Abdalvand A. Effects of Telestroke on Thrombolysis Times and Outcomes: A Meta-analysis. Prehosp Emerg Care. 2018 Jul-Aug; 22(4):472-484. PMID: 29345529.
17. Saad AM, Abushouk AI, Al-Husseini MJ, Salahia S, Alrefai A, Afifi AM, Abdel-Daim MM. Characteristics, survival and incidence rates and trends of primary cardiac malignancies in the United States. Cardiovasc Pathol. 2018 Mar - Apr; 33:27-31. PMID: 29414429.
18. Abushouk AI, El-Husseny MWA, Bahbah EI, Elmaraezy A, Ali AA, Ashraf A, Abdel-Daim MM. Peroxisome proliferator-activated receptors as therapeutic targets for heart failure. Biomed Pharmacother. 2017 Nov; 95:692-700. PMID: 28886529.
19. Elmaraezy A, Ismail A, Abushouk AI, Eltoomy M, Saad S, Negida A, Abdelaty OM, Abdallah AR, Aboelfotoh AM, Hassan HM, Elmaraezy AG, Morsi M, Althaher F, Althaher M, AlSafadi AM. Efficacy and safety of transcatheter aortic valve replacement in aortic stenosis patients at low to moderate surgical risk: a comprehensive meta-analysis. BMC Cardiovasc Disord. 2017 08 24; 17(1):234. PMID: 28836953.
20. Abdel-Daim MM, Khalifa HA, Abushouk AI, Dkhil MA, Al-Quraishy SA. Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice. Oxid Med Cell Longev. 2017; 2017:3281670. PMID: 28819543.
21. Shaban S, El-Husseny MWA, Abushouk AI, Salem AMA, Mamdouh M, Abdel-Daim MM. Effects of Antioxidant Supplements on the Survival and Differentiation of Stem Cells. Oxid Med Cell Longev. 2017; 2017:5032102. PMID: 28770021.
22. Ismail A, Abushouk AI, Bekhet AH, Abunar O, Hassan O, Khamis AA, Al-Sayed M, Elgebaly A. Regional versus local anesthesia for arteriovenous fistula creation in end-stage renal disease: a systematic review and meta-analysis. J Vasc Access. 2017 May 15; 18(3):177-184. PMID: 28478618.
23. Abushouk AI, Ismail A, Salem AMA, Afifi AM, Abdel-Daim MM. Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity. Biomed Pharmacother. 2017 Jun; 90:935-946. PMID: 28460429.
24. El Husseny MW, Mamdouh M, Shaban S, Ibrahim Abushouk A, Zaki MM, Ahmed OM, Abdel-Daim MM. Adipokines: Potential Therapeutic Targets for Vascular Dysfunction in Type II Diabetes Mellitus and Obesity. J Diabetes Res. 2017; 2017:8095926. PMID: 28286779.
25. Elmaraezy A, Abushouk AI, Saad S, Eltoomy M, Mahmoud O, Hassan HM, Aboelmakarem A, Fotoh AA, Althaher F, Huy NT, Hirayama K. Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Metaanalysis of Randomized Controlled Trials. CNS Neurol Disord Drug Targets. 2017; 16(7):789-799. PMID: 27978795.
26. Rahim-Taleghani S, Fatemi A, Alavi Moghaddam M, Shojaee M, Abushouk AI, Forouzanfar MM, Baratloo A. Correlation of central venous pressure with venous blood gas analysis parameters; a diagnostic study. Turk J Emerg Med. 2017 Mar; 17(1):7-11. PMID: 28345066.

Authored Pages

• Dilated Cardiomyopathy
• Dressler's Syndrome
• Beriberi