Sepsis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]

Overview

In the United States, sepsis is the leading cause of death in non-coronary ICU patients

It is a major cause of death in intensive care units worldwide, with mortality rates that range from 20% for sepsis to 40% for severe sepsis to > 60% for septic shock.

It is the tenth most common cause of death overall according to data from the Centers for Disease Control and Prevention.^[1]

Commoner in African Americans compared to other races in United States.

Common in winter compared to other seasons.

Sepsis is common and also more dangerous in elderly, immunocompromised, and critically ill patients.
It occurs in 1%-2% of all hospitalizations and accounts for as much as 25% of intensive care unit (ICU) bed utilization.

↑ Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003 Apr 17;348(16):1546-54. PMID 12700374 Full Text.