TINF2
TERF1 (TRF1)-interacting nuclear factor 2 | |||||||||||
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Identifiers | |||||||||||
Symbols | TINF2 ; TIN2 | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 8264 | ||||||||||
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Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
TERF1 (TRF1)-interacting nuclear factor 2, also known as TINF2, is a human gene.[1]
References
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Kim SH, Kaminker P, Campisi J (1999). "TIN2, a new regulator of telomere length in human cells". Nat. Genet. 23 (4): 405–12. doi:10.1038/70508. PMID 10581025.
- Li B, Oestreich S, de Lange T (2000). "Identification of human Rap1: implications for telomere evolution". Cell. 101 (5): 471–83. PMID 10850490.
- Mignon-Ravix C, Depetris D, Delobel B; et al. (2002). "A human interstitial telomere associates in vivo with specific TRF2 and TIN2 proteins". Eur. J. Hum. Genet. 10 (2): 107–12. doi:10.1038/sj.ejhg.5200775. PMID 11938440.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Yamada M, Tsuji N, Nakamura M; et al. (2003). "Down-regulation of TRF1, TRF2 and TIN2 genes is important to maintain telomeric DNA for gastric cancers". Anticancer Res. 22 (6A): 3303–7. PMID 12530079.
- Loayza D, De Lange T (2003). "POT1 as a terminal transducer of TRF1 telomere length control". Nature. 423 (6943): 1013–8. doi:10.1038/nature01688. PMID 12768206.
- Kim SH, Han S, You YH; et al. (2004). "The human telomere-associated protein TIN2 stimulates interactions between telomeric DNA tracts in vitro". EMBO Rep. 4 (7): 685–91. doi:10.1038/sj.embor.embor872. PMID 12835755.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Loayza D, Parsons H, Donigian J; et al. (2004). "DNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sites". J. Biol. Chem. 279 (13): 13241–8. doi:10.1074/jbc.M312309200. PMID 14715659.
- Ye JZ, de Lange T (2004). "TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex". Nat. Genet. 36 (6): 618–23. doi:10.1038/ng1360. PMID 15133513.
- Liu D, Safari A, O'Connor MS; et al. (2004). "PTOP interacts with POT1 and regulates its localization to telomeres". Nat. Cell Biol. 6 (7): 673–80. doi:10.1038/ncb1142. PMID 15181449.
- Ye JZ, Hockemeyer D, Krutchinsky AN; et al. (2004). "POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex". Genes Dev. 18 (14): 1649–54. doi:10.1101/gad.1215404. PMID 15231715.
- Kim SH, Beausejour C, Davalos AR; et al. (2004). "TIN2 mediates functions of TRF2 at human telomeres". J. Biol. Chem. 279 (42): 43799–804. doi:10.1074/jbc.M408650200. PMID 15292264.
- Ye JZ, Donigian JR, van Overbeek M; et al. (2004). "TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres". J. Biol. Chem. 279 (45): 47264–71. doi:10.1074/jbc.M409047200. PMID 15316005.
- Liu D, O'Connor MS, Qin J, Songyang Z (2005). "Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins". J. Biol. Chem. 279 (49): 51338–42. doi:10.1074/jbc.M409293200. PMID 15383534.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Oh BK, Kim YJ, Park C, Park YN (2005). "Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis". Am. J. Pathol. 166 (1): 73–80. PMID 15632001.
- Kaminker P, Plachot C, Kim SH; et al. (2005). "Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2". J. Cell. Sci. 118 (Pt 6): 1321–30. doi:10.1242/jcs.01709. PMID 15741234.
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