SYT2
| Synaptotagmin II | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SYT2 ; SytII | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 22516 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SYT2 214903 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Synaptotagmin II, also known as SYT2, is a human gene.[1]
References
Further reading
- Jones JM, Popma SJ, Mizuta M; et al. (1995). "Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19". Mamm. Genome. 6 (3): 212–3. PMID 7749232.
- Fukuda M, Aruga J, Niinobe M; et al. (1994). "Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II". J. Biol. Chem. 269 (46): 29206–11. PMID 7961887.
- Perin MS (1996). "Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin". Biochemistry. 35 (43): 13808–16. doi:10.1021/bi960853x. PMID 8901523.
- Baram D, Adachi R, Medalia O; et al. (1999). "Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells". J. Exp. Med. 189 (10): 1649–58. PMID 10330444.
- Mizutani A, Fukuda M, Ibata K; et al. (2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". J. Biol. Chem. 275 (13): 9823–31. PMID 10734137.
- Kida Y, Sakaguchi M, Fukuda M; et al. (2000). "Membrane topogenesis of a type I signal-anchor protein, mouse synaptotagmin II, on the endoplasmic reticulum". J. Cell Biol. 150 (4): 719–30. PMID 10952998.
- Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS (2001). "Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery". J. Cell Biol. 153 (5): 1111–20. PMID 11381094.
- Kida Y, Sakaguchi M, Fukuda M; et al. (2001). "Amino acid residues before the hydrophobic region which are critical for membrane translocation of the N-terminal domain of synaptotagmin II". FEBS Lett. 507 (3): 341–5. PMID 11696368.
- Lindmark IM, Karlsson A, Serrander L; et al. (2002). "Synaptotagmin II could confer Ca(2+) sensitivity to phagocytosis in human neutrophils". Biochim. Biophys. Acta. 1590 (1–3): 159–66. PMID 12063179.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Rickman C, Archer DA, Meunier FA; et al. (2004). "Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate". J. Biol. Chem. 279 (13): 12574–9. doi:10.1074/jbc.M310710200. PMID 14709554.
- Lee BH, Min X, Heise CJ; et al. (2004). "WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding". Mol. Cell. 15 (5): 741–51. doi:10.1016/j.molcel.2004.07.018. PMID 15350218.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
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