SYNGAP1

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Synaptic Ras GTPase activating protein 1 homolog (rat)
Identifiers
Symbols SYNGAP1 ; RASA1; DKFZp761G1421; KIAA1938; RASA5; SYNGAP
External IDs Template:OMIM5 Template:MGI HomoloGene84739
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Synaptic Ras GTPase activating protein 1 homolog (rat), also known as SYNGAP1, is a human gene.[1]


References

  1. "Entrez Gene: SYNGAP1 synaptic Ras GTPase activating protein 1 homolog (rat)".

Further reading

  • Fantl WJ, Escobedo JA, Martin GA; et al. (1992). "Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways". Cell. 69 (3): 413–23. PMID 1374684.
  • Kroll J, Waltenberger J (1998). "The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells". J. Biol. Chem. 272 (51): 32521–7. PMID 9405464.
  • Kim JH, Liao D, Lau LF, Huganir RL (1998). "SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family". Neuron. 20 (4): 683–91. PMID 9581761.
  • Chen HJ, Rojas-Soto M, Oguni A, Kennedy MB (1998). "A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II". Neuron. 20 (5): 895–904. PMID 9620694.
  • Husi H, Ward MA, Choudhary JS; et al. (2000). "Proteomic analysis of NMDA receptor-adhesion protein signaling complexes". Nat. Neurosci. 3 (7): 661–9. doi:10.1038/76615. PMID 10862698.
  • Li W, Okano A, Tian QB; et al. (2001). "Characterization of a novel synGAP isoform, synGAP-beta". J. Biol. Chem. 276 (24): 21417–24. doi:10.1074/jbc.M010744200. PMID 11278737.
  • Pei L, Teves RL, Wallace MC, Gurd JW (2001). "Transient cerebral ischemia increases tyrosine phosphorylation of the synaptic RAS-GTPase activating protein, SynGAP". J. Cereb. Blood Flow Metab. 21 (8): 955–63. doi:10.1097/00004647-200108000-00008. PMID 11487731.
  • Nagase T, Kikuno R, Ohara O (2002). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res. 8 (4): 179–87. PMID 11572484.
  • Yi J, Kloeker S, Jensen CC; et al. (2002). "Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers". J. Biol. Chem. 277 (11): 9580–9. doi:10.1074/jbc.M106922200. PMID 11782456.
  • Kim JH, Lee HK, Takamiya K, Huganir RL (2003). "The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity". J. Neurosci. 23 (4): 1119–24. PMID 12598599.
  • Song B, Meng F, Yan X; et al. (2003). "Cerebral ischemia immediately increases serine phosphorylation of the synaptic RAS-GTPase activating protein SynGAP by calcium/calmodulin-dependent protein kinase II alpha in hippocampus of rats". Neurosci. Lett. 349 (3): 183–6. PMID 12951199.
  • Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Oh JS, Manzerra P, Kennedy MB (2004). "Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II". J. Biol. Chem. 279 (17): 17980–8. doi:10.1074/jbc.M314109200. PMID 14970204.
  • Tomoda T, Kim JH, Zhan C, Hatten ME (2004). "Role of Unc51.1 and its binding partners in CNS axon outgrowth". Genes Dev. 18 (5): 541–58. doi:10.1101/gad.1151204. PMID 15014045.
  • Song B, Yan XB, Zhang GY (2004). "PSD-95 promotes CaMKII-catalyzed serine phosphorylation of the synaptic RAS-GTPase activating protein SynGAP after transient brain ischemia in rat hippocampus". Brain Res. 1005 (1–2): 44–50. doi:10.1016/j.brainres.2004.01.032. PMID 15044063.
  • Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
  • Krapivinsky G, Medina I, Krapivinsky L; et al. (2004). "SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation". Neuron. 43 (4): 563–74. doi:10.1016/j.neuron.2004.08.003. PMID 15312654.
  • Jaffe H, Vinade L, Dosemeci A (2004). "Identification of novel phosphorylation sites on postsynaptic density proteins". Biochem. Biophys. Res. Commun. 321 (1): 210–8. doi:10.1016/j.bbrc.2004.06.122. PMID 15358237.

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