SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
Identifiers
Symbols	SMARCA1 ; ISWI; NURF140; SNF2L; SNF2L1; SNF2LB; SWI; SWI2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55711
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SMARCA1 203874 s at tn.png
File:PBB GE SMARCA1 203875 at tn.png
File:PBB GE SMARCA1 215294 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1, also known as SMARCA1, is a human gene.

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Two transcript variants encoding different isoforms have been found for this gene.

Further reading

• Okabe I, Bailey LC, Attree O; et al. (1992). "Cloning of human and bovine homologs of SNF2/SWI2: a global activator of transcription in yeast S. cerevisiae". Nucleic Acids Res. 20 (17): 4649–55. PMID 1408766.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bozhenok L, Wade PA, Varga-Weisz P (2002). "WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci". EMBO J. 21 (9): 2231–41. doi:10.1093/emboj/21.9.2231. PMID 11980720.CS1 maint: Multiple names: authors list (link)
• Maguire PB, Wynne KJ, Harney DF; et al. (2003). "Identification of the phosphotyrosine proteome from thrombin activated platelets". Proteomics. 2 (6): 642–8. doi:10.1002/1615-9861(200206)2:6<642::AID-PROT642>3.0.CO;2-I. PMID 12112843.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Barak O, Lazzaro MA, Lane WS; et al. (2004). "Isolation of human NURF: a regulator of Engrailed gene expression". EMBO J. 22 (22): 6089–100. doi:10.1093/emboj/cdg582. PMID 14609955.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Barak O, Lazzaro MA, Cooch NS; et al. (2004). "A tissue-specific, naturally occurring human SNF2L variant inactivates chromatin remodeling". J. Biol. Chem. 279 (43): 45130–8. doi:10.1074/jbc.M406212200. PMID 15310751.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang F, Zhang R, Beischlag TV; et al. (2004). "Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene". J. Biol. Chem. 279 (45): 46733–41. doi:10.1074/jbc.M409002200. PMID 15347669.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Banting GS, Barak O, Ames TM; et al. (2005). "CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L". Hum. Mol. Genet. 14 (4): 513–24. doi:10.1093/hmg/ddi048. PMID 15640247.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ross MT, Grafham DV, Coffey AJ; et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lazzaro MA, Pépin D, Pescador N; et al. (2006). "The imitation switch protein SNF2L regulates steroidogenic acute regulatory protein expression during terminal differentiation of ovarian granulosa cells". Mol. Endocrinol. 20 (10): 2406–17. doi:10.1210/me.2005-0213. PMID 16740656.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)