PPP4C

Protein phosphatase 4 (formerly X), catalytic subunit
Identifiers
Symbols	PPP4C ; PP4; PPH3; PPX
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2038
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE PPP4C 208932 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Protein phosphatase 4 (formerly X), catalytic subunit, also known as PPP4C, is a human gene.

Further reading

• Brewis ND, Cohen PT (1993). "Protein phosphatase X has been highly conserved during mammalian evolution". Biochim. Biophys. Acta. 1171 (2): 231–3. PMID 1336397.
• Brewis ND, Street AJ, Prescott AR, Cohen PT (1993). "PPX, a novel protein serine/threonine phosphatase localized to centrosomes". EMBO J. 12 (3): 987–96. PMID 8384557.CS1 maint: Multiple names: authors list (link)
• Bastians H, Krebber H, Hoheisel J; et al. (1997). "Assignment of the human serine/threonine protein phosphatase 4 gene (PPP4C) to chromosome 16p11-p12 by fluorescence in situ hybridization". Genomics. 42 (1): 181–2. doi:10.1006/geno.1997.4693. PMID 9177794.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kloeker S, Bryant JC, Strack S; et al. (1997). "Carboxymethylation of nuclear protein serine/threonine phosphatase X.". Biochem. J. 327 ( Pt 2): 481–6. PMID 9359419.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen J, Peterson RT, Schreiber SL (1998). "Alpha 4 associates with protein phosphatases 2A, 4, and 6". Biochem. Biophys. Res. Commun. 247 (3): 827–32. doi:10.1006/bbrc.1998.8792. PMID 9647778.CS1 maint: Multiple names: authors list (link)
• Hu MC, Tang-Oxley Q, Qiu WR; et al. (1999). "Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity". J. Biol. Chem. 273 (50): 33561–5. PMID 9837938.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kloeker S, Wadzinski BE (1999). "Purification and identification of a novel subunit of protein serine/threonine phosphatase 4". J. Biol. Chem. 274 (9): 5339–47. PMID 10026142.
• Hastie CJ, Carnegie GK, Morrice N, Cohen PT (2000). "A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres". Biochem. J. 347 Pt 3: 845–55. PMID 10769191.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Carnegie GK, Sleeman JE, Morrice N; et al. (2004). "Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs". J. Cell. Sci. 116 (Pt 10): 1905–13. doi:10.1242/jcs.00409. PMID 12668731.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yeh PY, Yeh KH, Chuang SE; et al. (2004). "Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation". J. Biol. Chem. 279 (25): 26143–8. doi:10.1074/jbc.M402362200. PMID 15073167.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mihindukulasuriya KA, Zhou G, Qin J, Tan TH (2004). "Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation". J. Biol. Chem. 279 (45): 46588–94. doi:10.1074/jbc.M408067200. PMID 15331607.CS1 maint: Multiple names: authors list (link)
• Zhou G, Boomer JS, Tan TH (2005). "Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1". J. Biol. Chem. 279 (47): 49551–61. doi:10.1074/jbc.M410317200. PMID 15364934.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang X, Ozawa Y, Lee H; et al. (2005). "Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4". Genes Dev. 19 (7): 827–39. doi:10.1101/gad.1286005. PMID 15805470.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)