PPP1R2

Protein phosphatase 1, regulatory (inhibitor) subunit 2
Identifiers
Symbols	PPP1R2 ; IPP2; MGC87148
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4546
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE PPP1R2 202165 at tn.png
File:PBB GE PPP1R2 202166 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Protein phosphatase 1, regulatory (inhibitor) subunit 2, also known as PPP1R2, is a human gene.

Further reading

• Sanséau P, Jackson A, Alderton RP; et al. (1994). "Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences". Mamm. Genome. 5 (8): 490–6. PMID 7949733.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Helps NR, Street AJ, Elledge SJ, Cohen PT (1994). "Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli". FEBS Lett. 340 (1–2): 93–8. PMID 8119416.CS1 maint: Multiple names: authors list (link)
• Park IK, Roach P, Bondor J; et al. (1994). "Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2". J. Biol. Chem. 269 (2): 944–54. PMID 8288648.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Permana PA, Mott DM (1997). "Genetic analysis of human type 1 protein phosphatase inhibitor 2 in insulin-resistant Pima Indians". Genomics. 41 (1): 110–4. doi:10.1006/geno.1997.4649. PMID 9126490.
• Kakinoki Y, Somers J, Brautigan DL (1998). "Multisite phosphorylation and the nuclear localization of phosphatase inhibitor 2-green fluorescent protein fusion protein during S phase of the cell growth cycle". J. Biol. Chem. 272 (51): 32308–14. PMID 9405437.CS1 maint: Multiple names: authors list (link)
• Yang J, Hurley TD, DePaoli-Roach AA (2000). "Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif". J. Biol. Chem. 275 (30): 22635–44. doi:10.1074/jbc.M003082200. PMID 10807923.CS1 maint: Multiple names: authors list (link)
• Agarwal-Mawal A, Paudel HK (2001). "Neuronal Cdc2-like protein kinase (Cdk5/p25) is associated with protein phosphatase 1 and phosphorylates inhibitor-2". J. Biol. Chem. 276 (26): 23712–8. doi:10.1074/jbc.M010002200. PMID 11320080.
• Eto M, Elliott E, Prickett TD, Brautigan DL (2003). "Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation". J. Biol. Chem. 277 (46): 44013–20. doi:10.1074/jbc.M208035200. PMID 12221103.CS1 maint: Multiple names: authors list (link)
• Terry-Lorenzo RT, Elliot E, Weiser DC; et al. (2003). "Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton". J. Biol. Chem. 277 (48): 46535–43. doi:10.1074/jbc.M206960200. PMID 12270929.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang H, Brautigan DL (2003). "A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2". J. Biol. Chem. 277 (51): 49605–12. doi:10.1074/jbc.M209335200. PMID 12393858.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gevaert K, Goethals M, Martens L; et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Leach C, Shenolikar S, Brautigan DL (2003). "Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis". J. Biol. Chem. 278 (28): 26015–20. doi:10.1074/jbc.M300782200. PMID 12697755.CS1 maint: Multiple names: authors list (link)
• Sakashita G, Shima H, Komatsu M; et al. (2004). "Regulation of type 1 protein phosphatase/inhibitor-2 complex by glycogen synthase kinase-3beta in intact cells". J. Biochem. 133 (2): 165–71. PMID 12761178.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamada M, Ikeda Y, Yano M; et al. (2006). "Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy". FASEB J. 20 (8): 1197–9. doi:10.1096/fj.05-5299fje. PMID 16627625.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• King TD, Gandy JC, Bijur GN (2007). "The protein phosphatase-1/inhibitor-2 complex differentially regulates GSK3 dephosphorylation and increases sarcoplasmic/endoplasmic reticulum calcium ATPase 2 levels". Exp. Cell Res. 312 (18): 3693–700. doi:10.1016/j.yexcr.2006.08.010. PMID 16987514.CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)