Hepatitis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Epidemiology and Demographics

• HAV, HBV, HCV, HDV (with co-existing HBV infection), and HEV causes 95% of total acute viral hepatitis in the United States. Pathogenicity of HGV in humans is unclear. The most common cause of acute hepatitis in the United States is HAV and HCV is the most common cause of chronic hepatitis.
• Fecal-oral route is the most common route of transmission for HAV and HEV.
• Parenteral transmission is common for HBV and HCV.
• HBV is commonly transmitted via sexual contact and perinatal transmission.