Calcinosis is the formation of calcium deposits in any soft tissue.

Types

Dystrophic calcification

The most common type of calcinosis is dystrophic calcification. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices.

Metastatic calcification

Metastatic calcification involves a systemic calcium-phosphate mineral imbalance, which can be caused by renal failure, milk-alkali syndrome, or other etiologies.

Tumoral calcinosis

The etiology of the rare condition of tumoral calcinosis is not entirely understood. It is generally characterized by large, globular calcifications near joints.

Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare autosomal recessive metabolic disorder.^[1] Its principal clinical features are represented by ectopic periarticular calcifications associated with elevated levels of serum phosphate.^[1]

References

	Calcinosis;
MeSH	D002114

↑ ^1.0 ^1.1 Barbieri AM, Filopanti M, Bua G, Beck-Peccoz P (2007). "Two novel nonsense mutations in GALNT3 gene are responsible for familial tumoral calcinosis". J Hum Genet. 52 (5): 464–8. PMID 17351710.

External links

Univ. Washington School of Medicine article on Soft Tissue Calcifications

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[Barbieri-1] 1.0 ^1.1 Barbieri AM, Filopanti M, Bua G, Beck-Peccoz P (2007). "Two novel nonsense mutations in GALNT3 gene are responsible for familial tumoral calcinosis". J Hum Genet. 52 (5): 464–8. PMID 17351710.

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Calcinosis

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