Appendix cancer other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

Positron emission tomography (PET) and scintigraphy are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer.

Other Imaging Findings

  • The followings are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer:
  • High sensitivity and specificity for both functioning and non-functioning carcinoid tumors
  • Most sensitive imaging method to evaluate extrahepatic metastases
  • Useful in treatment planning
  • Indicates response to octreotide analogues [1]
  • distinguish between primary and metastatic tumors.
  • Detecting carcinoid tumors that are negative on OctreoScan
Appendiceal adenocarcinoma complicated by retroperitoneal abscess. Post-operative PET-CT scan shows high uptake posterior to the cecum, suspicious for residual tumor and/or peritoneal carcinomatosis. Case courtesy of Dr Francis Fortin, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/58007">rID: 58007</a>

References

  1. Kisker O, Bartsch D, Weinel RJ, Joseph K, Welcke UH, Zaraca F et al. (1997) The value of somatostatin-receptor scintigraphy in newly diagnosed endocrine gastroenteropancreatic tumors. J Am Coll Surg 184 (5):487-92. PMID: 9145069
  2. Kaltsas G, Korbonits M, Heintz E, Mukherjee JJ, Jenkins PJ, Chew SL et al. (2001) Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors. J Clin Endocrinol Metab 86 (2):895-902. DOI:10.1210/jcem.86.2.7194 PMID: 11158063
  3. Sundin A, Eriksson B, Bergström M, Långström B, Oberg K, Orlefors H (2004) PET in the diagnosis of neuroendocrine tumors. Ann N Y Acad Sci 1014 ():246-57. PMID: 15153441

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