Disseminated intravascular coagulation historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]

Overview

The syndrome of DIC is well known in the medical literature for centuries, although a more precise description of the underlying mechanisms had to await the 20th century. Initial ideas on a role of the contact activation system as the primary trigger for the systemic activation of coagulation as well as a presumed hyperfibrinolytic response in DIC have been found to be misconceptions. [1]

Historical Perspective

Discovery

  • [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
  • The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
  • In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

Outbreaks

There have been several outbreaks of [disease name], which are summarized below:

Landmark Events in the Development of Treatment Strategies

In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

The following are a few famous cases of disease name:

References

  1. Levi M, van der Poll T (November 2014). "A short contemporary history of disseminated intravascular coagulation". Semin. Thromb. Hemost. 40 (8): 874–80. doi:10.1055/s-0034-1395155. PMID 25377321.


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