Polycystic kidney disease interventions
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
There are no recommended therapeutic interventions for the management of [disease name].
OR
[Name of intervention] is not the first-line treatment option for patients with [disease name]. [Name of intervention] is usually reserved for patients with either [indication 1], [indication 2], and [indication 3]
OR
The mainstay of treatment for [disease name] is medical therapy/surgery. [Name of intervention] is usually reserved for patients with either [indication 1], [indication 2], and/or [indication 3].
OR
The feasibility of [name of intervention] depends on the stage of [disease or malignancy] at the time of diagnosis.
OR
[Name of intervention] is the mainstay of treatment for [disease or malignancy].
Indications
Dialysis is not the first-line treatment option for patients with polycystic kidney disease. Dialysis is usually reserved for patients with either:[1]
- End stage renal disease (ESRD)
- Renal failure
Dialysis
- Dialysis is the mainstay of treatment for ESRD and renal failure in patients with polycystic kidney disease[2]
- Peritoneal dialysis is not preferred in patients with PKD, because of the lack of ability to acoomodate large volume of peritoneal fluid[3]
- Peritoneal dialysis is also avoided in patients with aortic aneurysms
- Peritoneal dialysis may have a survival benefit over hemodialysis[4]
- Hemodialysis is the preferred modality for renal replacement in patients with polycystic kidney disease[2]
- Anticoagulants required for hemodialysis should be used with caution due to pre existing hematuria
Contraindications
References
- ↑ Grantham JJ (October 2008). "Clinical practice. Autosomal dominant polycystic kidney disease". N. Engl. J. Med. 359 (14): 1477–85. doi:10.1056/NEJMcp0804458. PMID 18832246.
- ↑ 2.0 2.1 Pirson Y, Christophe JL, Goffin E (1996). "Outcome of renal replacement therapy in autosomal dominant polycystic kidney disease". Nephrol. Dial. Transplant. 11 Suppl 6: 24–8. PMID 9044324.
- ↑ Lederman ED, McCoy G, Conti DJ, Lee EC (February 2000). "Diverticulitis and polycystic kidney disease". Am Surg. 66 (2): 200–3. PMID 10695753.
- ↑ Abbott KC, Agodoa LY (March 2002). "Polycystic kidney disease at end-stage renal disease in the United States: patient characteristics and survival". Clin. Nephrol. 57 (3): 208–14. PMID 11924752.