Post-streptococcal glomerulonephritis natural history, complications and prognosis
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Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of post-streptococcal glomerulonephritis typically develop one to three weeks after exposure to group A streptococcal infection throat infection and 3 to 6 weeks after group A streptococcal infection skin infection.
- If left untreated, patients with post-streptococcal glomerulonephritis may progress to develop renal failure.[1]
Complications
Common complications of post-streptococcal glomerulonephritis include:[2][3][4]
- Severe nephritis
- Renal failure
- Atypical hemolytic-uremic syndrome
- Refractory hypoxic respiratory failure
- Seizures
Prognosis
- Prognosis is generally excellent, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of the tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Ayoob RM, Schwaderer AL (2016). "Acute Kidney Injury and Atypical Features during Pediatric Poststreptococcal Glomerulonephritis". Int J Nephrol. 2016: 5163065. doi:10.1155/2016/5163065. PMC 5011525. PMID 27642522.
- ↑ Kakajiwala A, Bhatti T, Kaplan BS, Ruebner RL, Copelovitch L (February 2016). "Post-streptococcal glomerulonephritis associated with atypical hemolytic uremic syndrome: to treat or not to treat with eculizumab?". Clin Kidney J. 9 (1): 90–6. doi:10.1093/ckj/sfv119. PMC 4720198. PMID 26798467.
- ↑ Mara-Koosham G, Stoltze K, Aday J, Rendon P (2016). "Pulmonary Renal Syndrome After Streptococcal Pharyngitis: A Case Report". J Investig Med High Impact Case Rep. 4 (2): 2324709616646127. doi:10.1177/2324709616646127. PMC 4871206. PMID 27231692.
- ↑ Adikari M, Priyangika D, Marasingha I, Thamotheram S, Premawansa G (September 2014). "Post-streptococcal glomerulonephritis leading to posterior reversible encephalopathy syndrome: a case report". BMC Res Notes. 7: 644. doi:10.1186/1756-0500-7-644. PMC 4175190. PMID 25218027.