Post-streptococcal glomerulonephritis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Laboratory findings consistent with the diagnosis of streptococcal infection include antistreptolysin O (ASO) positive, antinicotinamide adenine dinucleotides positive, antihyaluronidase, and anti–DNAse B positive. Other abnormal laboratory findings include leukocytosis with neutrophilia, CRP is raised, increased levels of blood urea nitrogen (BUN) and serum creatinine levels are increased. On serologic testing, hypocomplementemia is usually found. On urinalysis, proteinuria, hematuria, and dysmorphic red cells are usually found.

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References

  1. Lang MM, Towers C (August 2001). "Identifying poststreptococcal glomerulonephritis". Nurse Pract. 26 (8): 34, 37–42, 44–7, quiz 48–9. PMID 11521409.
  2. Kılıc BD, Kara MA, Buyukcelik M, Balat A (May 2018). "Evaluation of clinical and laboratory findings in pediatric post-streptococcal glomerulonephritis". Pediatr Int. doi:10.1111/ped.13587. PMID 29729114.
  3. Wyatt RJ, Forristal J, West CD, Sugimoto S, Curd JG (April 1988). "Complement profiles in acute post-streptococcal glomerulonephritis". Pediatr. Nephrol. 2 (2): 219–23. PMID 3153014.
  4. Cameron JS, Vick RM, Ogg CS, Seymour WM, Chantler C, Turner DR (September 1973). "Plasma C3 and C4 concentrations in management of glomerulonephritis". Br Med J. 3 (5882): 668–72. PMC 1587021. PMID 4200478.
  5. Luo C, Chen D, Tang Z, Zhou Y, Wang J, Liu Z, Li L (September 2010). "Clinicopathological features and prognosis of Chinese patients with acute post-streptococcal glomerulonephritis". Nephrology (Carlton). 15 (6): 625–31. doi:10.1111/j.1440-1797.2010.01352.x. PMID 20883283.

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