Kawasaki disease causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]

Overview

The exact cause of kawasaki disease has not been identified. The current etiological theories center primarily on immunological causes for the disease, much research is being performed to discover a definitive toxin or antigenic substance, possibly a superantigen, that is the specific cause of the disease. There are several hypothesis for the causes of Kawasaki disease, the Infectious agents which are thought to induce kawasaki disease are, parvovirus B19, meningococcal septicemia, adenovirus, bacterial toxin–mediated, superantigens, cytomegalovirus, epstein-Barr virus, human lymphotropic virus infection, klebsiella pneumoniae bacteremia, mycoplasma pneumoniae, mite-associated bacteria, measles, propionibacterium acnes, parainfluenza type 3 virus, rotavirus infection, rickettsia species and tick-borne diseases.

Causes

• The exact cause of kawasaki disease has not been identified.
• The current etiological theories center primarily on immunological causes for the disease.
• Much research is being performed to discover a definitive toxin or antigenic substance, possibly a superantigen, that is the specific cause of the disease.
• An unknown virus may play a role as an inciting factor as well.
• There are several hypothesis for the causes of Kawasaki disease, the Infectious agents which are thought to induce kawasaki disease are:
  • Parvovirus B19
  • Meningococcal septicemia
  • Adenovirus
  • Bacterial toxin–mediated superantigens
  • Cytomegalovirus
  • Epstein-Barr virus
  • Human lymphotropic virus infection
  • Klebsiella pneumoniae bacteremia
  • Mycoplasma pneumoniae
  • Mite-associated bacteria
  • Measles
  • Propionibacterium acnes
  • Parainfluenza type 3 virus
  • Rotavirus infection
  • Rickettsia species
  • Tick-borne diseases