Optic nerve glioma physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Common physical examination findings of optic nerve glioma include nystagmus, strabismus, proptosis, visual impairment, afferent pupillary defect, edema and/or pallor of optic disc, torticollis and deficits of cranial nerve II.

Physical Examination

Eyes

Head

Neurological

Skin

  • Café-au-lait spots or hyperpigmented macules may be present in patients with optic pathway glioma associated with NF-1.
  • Axillary or inguinal freckles may be present in patients with optic nerve glioma associated with NF-1.

References

  1. Lavery MA, O'Neill JF, Chu FC, Martyn LJ (1984). "Acquired nystagmus in early childhood: a presenting sign of intracranial tumor". Ophthalmology. 91 (5): 425–53. PMID 6739045.
  2. Arnoldi KA, Tychsen L (1995). "Prevalence of intracranial lesions in children initially diagnosed with disconjugate nystagmus (spasmus nutans)". J Pediatr Ophthalmol Strabismus. 32 (5): 296–301. PMID 8531033.
  3. Koenig SB, Naidich TP, Zaparackas Z (1982). "Optic glioma masquerading as spasmus nutans". J Pediatr Ophthalmol Strabismus. 19 (1): 20–4. PMID 7069562.

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