Chronic pancreatitis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

History and Symptoms

Patients with chronic pancreatitis usually present with:

  • Persistent abdominal pain with episodic flares may or may not be associated with food intake[1][2][3][4]. Typical features of pain are:
    • Located in the epigastrium
    • Radiating to the back
    • May be associated with nausea and vomiting
    • Usually worse 15-30min after meal
    • Initially it occurs in discrete episodes but later on as the disease progresses, it changes to continuous-like pattern
  • Steatorrhea resulting from malabsorption of the fats in food (greasy, loose, very bad smelling stools that are difficult to flush away)
  • Severe nausea
  • Weight loss

References

  1. Ammann RW, Akovbiantz A, Largiader F, Schueler G (1984). "Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients". Gastroenterology. 86 (5 Pt 1): 820–8. PMID 6706066.
  2. Lankisch PG, Seidensticker F, Löhr-Happe A, Otto J, Creutzfeldt W (1995). "The course of pain is the same in alcohol- and nonalcohol-induced chronic pancreatitis". Pancreas. 10 (4): 338–41. PMID 7792289.
  3. Warshaw AL (1984). "Pain in chronic pancreatitis. Patients, patience, and the impatient surgeon". Gastroenterology. 86 (5 Pt 1): 987–9. PMID 6706079.
  4. Layer P, Yamamoto H, Kalthoff L, Clain JE, Bakken LJ, DiMagno EP (1994). "The different courses of early- and late-onset idiopathic and alcoholic chronic pancreatitis". Gastroenterology. 107 (5): 1481–7. PMID 7926511.


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