Chronic pancreatitis pathophysiology

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Chronic pancreatitis Microchapters
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Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Chronic pancreatitis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
Diagnostic Criteria
History and Symptoms
Physical Examination
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Cost-Effectiveness of Therapy
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Case #1
American Pancreatic Association Practice Guidelines
APA Clinical Practice Guidelines for Chronic pancreatiits
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Pathophysiology

• Chronic pancreatitis is a progressive inflammatory process leading to irreversible structural damage to pancreas resulting in exocrine and endocrine dysfunction

Genetics

• [Disease name] is transmitted in [mode of genetic transmission] pattern.
• Genes involved in the pathogenesis of [disease name] include [gene1], [gene2], and [gene3].
• The development of [disease name] is the result of multiple genetic mutations.

Associated Conditions

Gross Pathology

• Patchy focal disease
• Fibrosis

Microscopic Pathology

• On microscopic histopathological analysis:
  • Patchy focal disease characterized by a mononuclear infiltrate
  • Fibrosis

References

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