Diabetes mellitus type 1 causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
The exact cause of type 1 DM remains unknown. Studies have found that cause of Type 1 DM is the result of interactions of genetic, environmental, and immunologic factors:
Type 1 Diabetes causes | |
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Genes associated with Type 1 DM | Candidate genes assoicated with type 1 diabetes are:
PTPN22, IL10, AFF3, IFIH1, STAT4, CTLA4, CCR5, IL21, IL2, IL7R, BACH2, TNFAIP3, TAGAP, IKZF1, GLIS3, IL2RA, PRKCQ, NRP1, INS, BAD, CD69, ITGB7, ERBB3, CYP27B1, SH2B3, GPR183, DLK1, RASGRP1, CTSH, CLEC16A, IL27, ORMDL3, PTPN2, CD226, TYK2, FUT2, and UBASK3A |
Envirnomental triggers associated with Type 1 DM |
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Immunologic factors associated with Type 1 DM |
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