Sickle-cell disease echocardiography or ultrasound

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]

Overview

Echocardiography and ultrasound have limited diagnostic value in sickle cell disease.

Echocardiography

In some cases, such as suspected heart failure, echocardiography may be warranted. In general, there is minimal use for echocardiography in patients with sickle cell disease. However, patients with pulmonary hypertension due to vaso-occlusive crisis in the lungs may benefit from echocardiography, since this test can provide some insight into right-sided heart pressures and pulmonary arterial pressures. [1] The pulmonary pressures can be estimated via echocardiography using the tricuspid jet velocity and the Bernoulli equation.

References

  1. Potoka KP, Gladwin MT (2015). "Vasculopathy and pulmonary hypertension in sickle cell disease". Am J Physiol Lung Cell Mol Physiol. 308 (4): L314–24. doi:10.1152/ajplung.00252.2014. PMC 4329471. PMID 25398989.

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