Bone or cartilage mass epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Primary bone and cartilage tumors are uncommon, these tumors represent 0.2% of all neoplasms in general population. The prevalence of bone and cartilage tumors is approximately 0.9 per 100,000 individuals. Primary bone and cartilage tumors affect primarily children and adolescents. The average age at diagnosis is between 10 and 25 years old. Males are more commonly affected than females, with a 2:1 ratio.[1] Bone and cartilage tumors are slightly more common among individuals of Caucasian race. Conversely, secondary bone tumors (metastases) are the most common malignant bone lesion seen in adults. Secondary bone tumors affect middle-age adult patients, more frequently. The average age at diagnosis is between 45 and 85 years old. Males and females are equally affected.[2]
Epidemiology and demographics
Prevalence
- Benign bone tumors represent 0.2% of all neoplasms in general population.
| Primary bone malignancy | Frequency (%) |
|---|---|
| Osteosarcoma | 35.1 |
| Chondrosarcoma | 25.8 |
| Ewing sarcoma | 16 |
| Chordoma | 8.4 |
| Malignant fibrous histiocytoma | 5.7 |
| Unespecifed | 1.2 |
| Others | 6.4 |
Incidence
- The incidence rate for all bone and cartilage malignant tumors is 0.9 per 100,000 persons per year.
Age
- The age adjusted incidence rate of malignant bone tumors has a bimodal distribution.