Chancroid differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Nate Michalak, B.A.; Serge Korjian M.D.

Overview

Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy including syphilis, herpes simplex, Behçet's disease, lymphogranuloma venereum, donovanosis, and fixed drug eruption.

Differential Diagnosis of Chancroid

Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy:

Syphilitic chancres most closely resemble and chancroid lesion. A comparison is found below:[1]

Clinical Characteristic Disease
Syphilitic Chancre Chancroid
Mode of Transmission Mainly sexual Mainly sexual
Cause Treponema pallidum Haemophilus ducreyi
Lesion Type Pustules that may progress to ulcers Pustules that may progress to ulcers
Lesion Pain Typically absent Typically present
Lesion Location Typically genitals Typically genitals; may occur on limbs
Lesion Size Typically 1-2 cm in diameter Typically 1-2 cm in diameter
Lesion Number Multiple 1-4
Lesion Exudate Typically non-exudative Typically grey/yellow purulent exudate
Lesion Tenderness Typically indurated Typically soft
Lymphadenopathy Typically present Occurs in approx. half of patients

References

  1. Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2016.


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